Patents Represented by Attorney K&L Gates, LLP
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Patent number: 8323928Abstract: Anti-lentivirus vaccines and immunotherapeutics and methods for preparing and using same are disclosed. The vaccines and immunotherapeutics are produced using non-immunosuppressive lentivirus trans-activator of transcription (Tat) proteins. An associated in vitro ultra-sensitive macrophage Tat bioassay is disclosed for assessing the immunosuppressive qualities of the lentivirus Tat preparations of the present invention. Additionally, a related long-term T4 cell propagation system for characterizing lentivirus Tat is also disclosed. The present invention has additional utility in the treatment and prevention of AIDS.Type: GrantFiled: March 24, 2006Date of Patent: December 4, 2012Assignee: PIN Pharma, Inc.Inventor: David I. Cohen
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Patent number: 8236267Abstract: The present invention discloses a high-pressure vessel of large size formed with a limited size of e.g. Ni—Cr based precipitation hardenable superalloy. The vessel may have multiple zones. For instance, the high-pressure vessel may be divided into at least three regions with flow-restricting devices and the crystallization region is set higher temperature than other regions. This structure helps to reliably seal both ends of the high-pressure vessel, and at the same time, may help to greatly reduce unfavorable precipitation of group III nitride at the bottom of the vessel. This invention also discloses novel procedures to grow crystals with improved purity, transparency and structural quality. Alkali metal-containing mineralizers are charged with minimum exposure to oxygen and moisture until the high-pressure vessel is filled with ammonia. Several methods to reduce oxygen contamination during the process steps are presented.Type: GrantFiled: June 4, 2009Date of Patent: August 7, 2012Assignee: Sixpoint Materials, Inc.Inventors: Tadao Hashimoto, Edward Letts, Masanori Ikari
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Patent number: 8217943Abstract: In accordance with the principles of the invention, methods, systems, and computer-readable mediums are provided for displaying cellular analysis result data including accessing cellular analysis result data, accessing data of at least one template, and displaying the cellular analysis result data and the data of at least one template by overlaying the cellular analysis result data and the data of the at least one template, wherein the cellular analysis result data is displayed using different display attributes from the displayed data of the at least one template.Type: GrantFiled: April 21, 2006Date of Patent: July 10, 2012Assignee: Beckman Coulter, Inc.Inventors: Cheng Qian, Ziling Huo, Patricio J. Vidal
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Patent number: 8142461Abstract: A surgical instrument that may include a housing, a transducer engaged with the housing which can produce vibrations, and an end-effector engaged with the transducer. The surgical instrument can further include an adjustable sheath extending from the housing where the sheath is movable relative to the distal tip of the end-effector and where the distance between the distal tip of the sheath and the distal tip of the end-effector can be set such that the sheath can act as a depth stop. The sheath can be adjusted such that, when the distal tip of the sheath contacts the tissue or bone being incised, the surgeon can determine that the appropriate depth of the incision has been reached. In other embodiments, the end-effector can be moved with respect to the sheath in order to adjust the distance between the distal tip of the end-effector and the distal tip of the sheath.Type: GrantFiled: March 22, 2007Date of Patent: March 27, 2012Assignee: Ethicon Endo-Surgery, Inc.Inventors: Kevin L. Houser, Andrew M. Zwolinski, Tracy D. Lopes, Prasanna Malaviya, Daniel W. Price, Louis T. DeLuca
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Patent number: 8083436Abstract: Disclosed herein are methods, devices and systems to maintain the accessibility and integrity of equipment contained in underground housings. The methods, devices and systems and methods of the present invention maintain the accessibility and integrity of equipment contained in underground housings by providing at least one barrier that prevents burrowing animals from off-loading displaced ground dirt or other debris into the space created by the underground housing.Type: GrantFiled: July 16, 2010Date of Patent: December 27, 2011Inventor: George W. Keeney
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Patent number: 8072105Abstract: An axial bearing for a high speed open-end spinning rotor mounted without axial thrust in a support disc bearing arrangement has a static magnetic bearing component secured in a bearing housing with at least two axially polarized permanent magnet rings limited by pole discs, and a dynamic magnetic bearing component having ferromagnetic webs on the rotor shaft at the spacing of the pole discs. The static magnetic bearing component (27) is arranged inside a plastic bearing bush (30) and secured by a plastic closing lid (31). The front side of the closing lid (31) has a stop journal (50) forming an axial emergency operation bearing and the rear side has a conically widened fastening lug (51) which is elastically deformed as installed.Type: GrantFiled: October 27, 2009Date of Patent: December 6, 2011Assignee: Oerlikon Textile GmbH & Co. KGInventor: Lothar Winzen
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Patent number: 8062600Abstract: An arrangement for separating coarse ash out of a flue gas stream, comprising a catalytic converter disposed in a widened flue gas channel portion and serving for reducing the NOx level in the flue gas stream. Also disposed in the widened channel portion is a separator sieve that extends essentially over the entire cross-section thereof. The separator sieve is provided with a plurality of openings for the passage of flue gas therethrough. Each opening has a cross-section that is smaller than a cross-section of coarse ash particles that are to be separated out.Type: GrantFiled: April 9, 2009Date of Patent: November 22, 2011Assignee: Evonik Energy Services GmbHInventors: Hermann Bruggendick, Wolfgang Benesch, Ralf Gilgen
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Patent number: 8063246Abstract: A method and apparatus is provided for cleaning flue gases from combustion plants. The method includes removing dust and removing nitrogen from flue gases, bringing flue gases into contact with an aqueous ammonia solution in the presence of an oxidizing agent whereby a reaction solution forms which contains at least ammonium carbonate, heating the reaction solution such that ammonium carbonate decomposes and carbon dioxide and ammonia transfer into the gas atmosphere, and reacting the gaseous carbon dioxide and the gaseous ammonia to form urea. The apparatus includes a device for removing nitrogen and removing dust from the flue gases, a washing device downstream of the device for removing nitrogen and removing dust, a stripper downstream of the washing device, and a urea installation downstream of the stripper.Type: GrantFiled: April 18, 2008Date of Patent: November 22, 2011Assignee: Evonik Energy Services GmbHInventor: Hermann Winkler
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Patent number: 8030278Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.Type: GrantFiled: February 20, 2009Date of Patent: October 4, 2011Assignees: Spectrum Pharmaceuticals, Inc., Board of Trustees University of IllinoisInventors: Anil Gulati, Guru Reddy, Luigi Lenaz
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Patent number: 8026216Abstract: Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).Type: GrantFiled: April 10, 2008Date of Patent: September 27, 2011Assignees: Spectrum Pharmaceuticals, Inc., Board of Trustees University of IllinoisInventors: Anil Gulati, Guru Reddy, Luigi Lenaz
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Patent number: 7806858Abstract: A retractable safety syringe is provided herein wherein an external vacuum compartment produces a retraction force which urges a piston of a plunger toward a retracted position. The retractable safety syringe may have a needle holder which is removably engageable to a distal portion of a syringe body. When the piston is traversed toward the engaged position, the external variable vacuum compartment produces a retraction force. When the piston is traversed to an engaged position, the piston engages the needle holder and disengages the needle holder from the syringe body. The medical professional may release a thumb pressure on a thumb platform of a plunger. At this point, the retraction force of the external variable vacuum compartment may traverse the piston along with the needle holder and needle toward the retracted position and into the syringe body. An internal variable vacuum compartment may also create a retraction force to assist retraction of the needle holder and needle into the syringe body.Type: GrantFiled: April 10, 2007Date of Patent: October 5, 2010Assignee: SafeShot Technologies, LLCInventors: Jeffrey Smith, Rex O. Bare
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Patent number: 7799735Abstract: A method for transferring a decorative sublimation dye design formed on a transfer sheet to a substrate. The method comprises providing a substrate treated with a melamine resin, chemically modifying the melamine resin to produce an active dye site for acceptance of a sublimation dye, and transferring the sublimation dye to the active dye site.Type: GrantFiled: May 31, 2006Date of Patent: September 21, 2010Inventors: Ronald Segall, Brian Sparks, Eric Batman
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Patent number: 7788894Abstract: A spindle bearing for a two-for-one twisting spindle, with a spindle rotor having a thread guide body and a spindle shaft rotatably mounted in a vertical arrangement by a lower bearing device in a bearing housing which can be fastened to a spindle bank and which has an upper bearing device for mounting a protective pot. A lubricant duct extends from the top through the thread guide body at least approximately parallel to the rotational axis of the spindle shaft and opens into the lower bearing device.Type: GrantFiled: July 5, 2006Date of Patent: September 7, 2010Assignee: Oerlikon Textile GmbH & Co. KGInventor: Heinz Fink
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Patent number: 7789198Abstract: A shoulder saddle for carrying a stepladder of the type having opposed, channel-shaped, side rails with spaced steps extending therebetween. A saddle block has a length no greater than the spacing between steps of the ladder and a width greater than the width of the ladder steps and has a top surface with a pair of spaced slots extending lengthwise therealong for receipt of the rail flanges. The bottom surface of the block is concave in lengthwise cross-section and has a layer of cushion material attached thereto. Relatively flat front and back portions are formed on the bottom surface beyond the concave cross-section to facilitate attachment of the cushion material.Type: GrantFiled: April 4, 2006Date of Patent: September 7, 2010Inventor: Paul E. Myers
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Patent number: 7784722Abstract: A stirring or dispersing device (1), has a hermetically sealed mixing chamber (5), a tool (2), and a drive mechanism (4) located outside of the mixing chamber (5). The tool (2) can be driven around a central shaft in the mixing chamber (5) which has a rod-shaped element (3) for force transmission from the drive mechanism (4) to the tool (2). The rod-shaped element (3) is connected at the entry to the mixing chamber (5) with a diaphragm (6), which is a part of the wall (7) of the mixing chamber (5), and the rod-shaped element (3) can be put into a wobbling movement by the drive mechanism (4), so that its end located in the interior of the mixing chamber (5) performs a rotating movement. The tool is constituted by a number of grinding elements (22) or balls to be introduced into the mixing chamber (5).Type: GrantFiled: April 27, 2006Date of Patent: August 31, 2010Assignee: IKA - Werke GmbH & Co. KGInventor: Peter Jägle
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Patent number: 7754230Abstract: Compositions and methods useful in the reduction of localized fat deposits in patients in need thereof using pharmacologically active detergents are disclosed. The pharmacologically active detergent compositions can additionally include anti-inflammatory agents, analgesics, dispersion or anti-dispersion agents and pharmaceutically acceptable excipients. The pharmacologically active detergent compositions are useful for treating localized accumulations of fat including, for example, lower eyelid fat herniation, lipodystrophy and fat deposits associated with cellulite and do not require surgical procedures such as liposuction.Type: GrantFiled: May 19, 2005Date of Patent: July 13, 2010Assignees: The Regents of the University of California, Los Angeles Biomed. Res. Inst. at Harbor UCLA Medical CenterInventors: Michael S. Kolodney, Adam M. Rotunda
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Patent number: 7752831Abstract: A system for activating a rotor drive (31) of an open-end rotor spinning machine (30), having an open-end rotor spinning machine (30) with a plurality of workstations (33), each having a rotor drive (31) with a control unit (4), which comprises at least one communication interface (18, 19) for connecting to a workstation control unit (35), and external means for substitute activation of the individual rotor drives (31) and for reading signals representing operating state data of the rotor drive from the individual control units (4) of the rotor drives (31) by means of at least one communication interface (18, 19) of the control units (4) for adjustment and checking purposes.Type: GrantFiled: August 14, 2008Date of Patent: July 13, 2010Assignee: Oerlikon Textile GmbH & Co. KGInventors: Nour-Eddine Balboul, Sven Meerkamp
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Patent number: 7749063Abstract: A bonus game that operates in combination with a slot machine base game is provided. The bonus game includes a series of free spins or free evaluations in which symbols of a set of symbols are generated. The free spins also generate executor symbols that alone or in accumulation cause one of the symbols of the set to be eliminated or replaced. In either case the symbols remaining in the set have a higher probability of being generated and a higher probability exists that a larger award paying combination of the remaining symbols will be generated. The elimination sequence can be repeated a number of times further increasing the probability of generating a higher paying award for the player. The present invention is operable with different types of base games such as slot and poker.Type: GrantFiled: September 29, 2004Date of Patent: July 6, 2010Assignee: IGTInventors: Matthew E. Belger, Karen M. Cregan
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Patent number: 7736741Abstract: A single-wall carbon nanotube heterojunction is provided. In the single-wall carbon nanotube, a semiconductive single-wall carbon nanotube and a metallic single-wall carbon nanotube are joined with each other in a longitudinal direction thereof.Type: GrantFiled: September 27, 2007Date of Patent: June 15, 2010Assignee: Sony CorporationInventors: Ryuchiro Maruyama, Toshinori Iwai, Hisashi Kajiura, Koji Kadono, Kenichi Kurihara
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Patent number: D624197Type: GrantFiled: February 18, 2010Date of Patent: September 21, 2010Assignee: Kewaunee Scientific CorporationInventors: Kurt P. Rindoks, Arturo Ramos, David Kendall Foote