Patents Represented by Attorney Karen B._ O'Connor
  • Patent number: 4382960
    Abstract: A novel cosmetic skin cleanser formulation is described which is non-irritating and non-stinging.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: May 10, 1983
    Assignee: Eli Lilly and Company
    Inventor: Merlyn G. Flom
  • Patent number: 4372944
    Abstract: A novel cosmetic skin cream formulation is described which is non-irritating and non-stinging.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: February 8, 1983
    Assignee: Eli Lilly and Company
    Inventor: Anne M. Herrold
  • Patent number: 4368187
    Abstract: A method of decreasing the sensitivity of the skin without causing irritation is described, using a four component cosmetic regime. The four components comprising the regime are: a cleanser, a toner, a moisturizer, and a cream.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: January 11, 1983
    Assignee: Eli Lilly and Company
    Inventors: Merlyn G. Flom, Anne M. Herrold, Joe O. Martin, Anton A. Mentlik, Patricia P. Warrick
  • Patent number: 4368188
    Abstract: A novel cosmetic skin toner formulation is described which is non-irritating and non-stinging.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: January 11, 1983
    Assignee: Eli Lilly and Company
    Inventor: Joe O. Martin
  • Patent number: 4368189
    Abstract: A novel cosmetic skin moisturizer formulation is described which is non-irritating and non-stinging.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: January 11, 1983
    Assignee: Eli Lilly and Company
    Inventor: Anton A. Mentlik
  • Patent number: 4364956
    Abstract: Compounds are described of the formula ##STR1## in which R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano, 5-tetrazolyl or 5-tetrazolylaminocarbonyl, where R.sup.5 is hydrogen or C.sub.1-6 alkyl; R.sup.2 is hydrogen or C.sub.1-6 alkyl; R.sup.3 is a group of the formulaR.sup.6 --(Z).sub.m --where m is O or 1, Z is O, S, SO, SO.sub.2 or CO, and R.sup.6 phenyl optionally substituted by one or more group selected from halogen, C.sub.1-4 alkyl, C.sub.3-6 cycloalkyl, C.sub.1-4 alkoxy, benzyloxy, hydroxy, nitro, C.sub.1-4 alkylthio, C.sub.1-4 alkylsulphinyl, C.sub.1-4 alkylsulphonyl, amino and NHR.sup.7 where R.sup.7 is C.sub.2-6 acyl; and R.sup.4 is hydrogen, C.sub.1-6 alkyl or halogen; and salts thereof. These compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.
    Type: Grant
    Filed: September 17, 1981
    Date of Patent: December 21, 1982
    Assignee: Lilly Industries Limited
    Inventors: Barry P. Clark, William J. Ross, Alec Todd
  • Patent number: 4362747
    Abstract: A novel cosmetic skin cream pack formulation is described which is non-irritating and non-stinging.
    Type: Grant
    Filed: August 3, 1981
    Date of Patent: December 7, 1982
    Assignee: Eli Lilly and Company
    Inventor: Lawrence J. Coursen
  • Patent number: 4356207
    Abstract: Dihydroxyphenoxy-1H-tetrazoles and their salts are used as non-nutritive sweeteners.
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: October 26, 1982
    Assignee: Eli Lilly and Company
    Inventor: William L. Garbrecht
  • Patent number: 4337341
    Abstract: 4a-phenyl and substituted phenyl 2,3,4,4a,5,6,7,7a-octahydro-1H-2-pyrindines having a 2-substituent are disclosed. Such compounds are useful as analgesic agents having mixed agonist and antagonist properties. The compounds can be prepared by reacting an amine with a 4-aryl-2,6-dioxocyclopenta[c]pyran, followed by reduction, or alternatively by alkylating a 4a-aryl-octahydro-1H-2-pyrindine at the 2-position.
    Type: Grant
    Filed: February 2, 1981
    Date of Patent: June 29, 1982
    Assignee: Eli Lilly and Company
    Inventor: Dennis M. Zimmerman
  • Patent number: 4322428
    Abstract: Novel triaryl thiazole compounds are useful as analgesic agents. In particular, 2-(4-halophenyl)-4,5-bis(4-methoxyphenyl)thiazoles are used. These compounds are prepared by condensation of a substituted thiobenzamide with a substituted desyl chloride.
    Type: Grant
    Filed: April 2, 1980
    Date of Patent: March 30, 1982
    Assignee: Eli Lilly and Company
    Inventors: Ken Matsumoto, Peter P. K. Ho
  • Patent number: 4309258
    Abstract: A method of isomerization is disclosed which converts the anti isomer of 1-isopropylsulfonyl-2-amino-6-(.alpha.-hydroxyiminobenzyl)benzimidazole to the syn isomer using photolysis.
    Type: Grant
    Filed: December 4, 1980
    Date of Patent: January 5, 1982
    Assignee: Eli Lilly and Company
    Inventor: James H. Wikel
  • Patent number: 4309446
    Abstract: Dihydroxyphenoxy-1H-tetrazoles and their salts are used as non-nutritive sweeteners.
    Type: Grant
    Filed: February 22, 1980
    Date of Patent: January 5, 1982
    Assignee: Eli Lilly and Company
    Inventor: William L. Garbrecht
  • Patent number: 4304728
    Abstract: Compounds are described of the formula ##STR1## in which R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano, 5-tetrazolyl or R.sup.6, where R.sup.5 is hydrogen or C.sub.1-8 alkyl and R.sup.6 is phenyl or naphthyl, the phenyl or naphthyl group being optionally substituted by one or more group selected from halogen, C.sub.1-6 alkyl, C.sub.1-4 alkoxy, hydroxy, benzyloxy, nitro, trifluoromethyl, carboxyl, C.sub.1-4 alkylsulphinyl, C.sub.1-4 alkylsulphonyl, N(R.sup.5).sub.2, NHCOR.sup.5 and SR.sup.5 ; R.sup.2 is R.sup.6 or --CH.dbd.CH--R.sup.6 when R.sup.1 is COOR.sup.5, CONHR.sup.5, cyano or 5-tetrazolyl, or R.sup.2 is --CH.dbd.CH--R.sup.6 when R.sup.1 is R.sup.6 ; R.sup.3 is hydrogen, C.sub.1-6 alkyl, halogen, hydroxy or --OCH.sub.2 R.sup.6 ; and R.sup.4 is hydrogen, C.sub.1-6 alkyl or halogen; and salts thereof. The compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.
    Type: Grant
    Filed: March 27, 1980
    Date of Patent: December 8, 1981
    Assignee: Lilly Industries Limited
    Inventors: Barry P. Clark, William J. Ross, Alec Todd
  • Patent number: 4289778
    Abstract: 2-(Substituted imino)-N-(3-substituted phenyl)-3-thiazolidinecarbothioamides, useful as insecticides.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: September 15, 1981
    Assignee: Eli Lilly and Company
    Inventor: Terry W. Balko
  • Patent number: 4289766
    Abstract: 2-Substituted-N-(3-substituted phenyl)thiazolidine-, tetrahydro-2H-1,3-thiazine-, and benzothiazoline-3-carbothioamides, useful as insecticides.
    Type: Grant
    Filed: December 27, 1977
    Date of Patent: September 15, 1981
    Assignee: Eli Lilly and Company
    Inventors: Terry W. Balko, Ronald E. Hackler
  • Patent number: 4278570
    Abstract: A skin cleanser formulation, which is one of four components used in a cosmetic regime, is disclosed. Applying the regime to the skin increases epidermal cell turnover without skin irritation. The other three components used in the regime are a cream, a lotion, and a tonic.
    Type: Grant
    Filed: August 20, 1980
    Date of Patent: July 14, 1981
    Assignee: Eli Lilly and Company
    Inventor: Merlyn G. Flom
  • Patent number: 4275210
    Abstract: Compositions comprising certain 2-(substituted anilino)benzoxazoles, such as 2-[4-bromo-3-(trifluoromethyl)-anilino]benzoxazole, and methods for using same as immunosuppressive agents, antifertility agents, for the prophylaxis of Marek's disease in chickens and as herbicides.
    Type: Grant
    Filed: February 15, 1978
    Date of Patent: June 23, 1981
    Assignee: Eli Lilly and Company
    Inventor: Charles J. Paget, Jr.
  • Patent number: 4272544
    Abstract: A novel cell renewal cosmetic regime is disclosed, which increases epidermal cell turnover without skin irritation. The regime consists of the use of four components: a cleanser, a cream, a lotion, and a tonic.
    Type: Grant
    Filed: August 20, 1980
    Date of Patent: June 9, 1981
    Assignee: Eli Lilly and Company
    Inventors: John A. Cella, Merlyn G. Flom, Anne M. Herrold, Joe O. Martin, Ovidio Vargas
  • Patent number: 4272519
    Abstract: A skin lotion formulation, which is one of four components used in a cosmetic regime, is disclosed. Applying the regime to the skin increases epidermal cell turnover without skin irritation. The other three components used in the regime are a cleanser, a cream, and a tonic.
    Type: Grant
    Filed: August 20, 1980
    Date of Patent: June 9, 1981
    Assignee: Eli Lilly and Company
    Inventors: Anne M. Herrold, Ovidio Vargas
  • Patent number: 4268502
    Abstract: A skin tonic formulation, which is one of four components used in a cosmetic regime, is disclosed. Applying the regime to the skin increases epidermal cell turnover without skin irritation. The other three components used in the regime are a cleanser, a cream, and a lotion.
    Type: Grant
    Filed: August 20, 1980
    Date of Patent: May 19, 1981
    Assignee: Eli Lilly and Company
    Inventor: Joe O. Martin