Patents Represented by Attorney, Agent or Law Firm Karen I. Krupen
  • Production of Aspergillus niger catalase-R
    Patent number: 5360732
    Abstract: The invention discloses the application of genetic engineering techniques to create novel strains of A. niger which produce high levels of catalase (catR gene product, catalase-R) while generating minimal sodium gluconate waste material.
    Type: Grant
    Filed: March 4, 1992
    Date of Patent: November 1, 1994
    Assignee: Genecor International, Inc.
    Inventors: Randy M. Berka, Timothy Fowler, Michael W. Rey
  • Methods for isolating EG III cellulase component and EG III cellulase in polyethylene glycol using inorganic salt and polyethylene glycol
    Patent number: 5328841
    Abstract: Methods for isolating EG III cellulase component and enriched EG III cellulase in polyethylene glycol are disclosed. The methods comprise adding an inorganic salt and polyethylene glycol having a molecular weight of from about 5,000 to 10,000 to an aqueous mixture of cellulase proteins under conditions to create a two-phase system. Next, the cellulase proteins other than EG III are separated in an EG III-poor aqueous phase while EG III cellulase component is retained in an EG III-rich polyethylene glycol phase. Lastly, the EG III component can be separated from the polyethylene glycol. The preferred method of separation is alcohol precipitation.
    Type: Grant
    Filed: April 3, 1992
    Date of Patent: July 12, 1994
    Assignee: Genencor International, Inc.
    Inventors: Jeffrey D. Lorch, Kathleen A. Clarkson, Edmund Larenas, Benjamin S. Bower, Geoffrey L. Weiss