Abstract: Compounds or formula (I), wherein R.sup.1 represents an n-propoxy, cyclobutoxy, cyclopropylamino, piperidino or pyrrolidino group; or a physiologically functional derivative thereof. The invention further includes methods for the preparation of compounds of formula (I), compositions containing them and the use of these compounds as antiviral agents.
Type:
Grant
Filed:
October 5, 1994
Date of Patent:
June 10, 1997
Assignee:
Glaxo Wellcome Inc.
Inventors:
Charlene L. Burns, George W. Koszalka, Thomas A. Krenitsky, Susan M. Daluge
Abstract: A method for treating HIV infections comprising administering a composition whose active ingredient is 2',3'-dideoxy-3'-fluoro-5'-chlorouridine.
Type:
Grant
Filed:
May 17, 1993
Date of Patent:
November 12, 1996
Assignee:
Glaxo Wellcome Inc.
Inventors:
Joel Van Tuttle, Susan M. Daluge, Charlene L. Burns, George W. Koszalka, Thomas A. Krenitsky