Patents Represented by Attorney Karen Lech Elbing

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  • DNA aptamers and catalysts that bind adenosine or adenosine-5'-phosphates and methods for isolation thereof
    Patent number: 5631146
    Abstract: Disclosed are single-stranded DNA molecules which bind adenosine or an adenosine-5'-phosphate and methods for their production and isolation. Also disclosed are methods for producing and isolating related catalytic DNA molecules.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: May 20, 1997
    Assignee: The General Hospital Corporation
    Inventors: Jack W. Szostak, David E. Huizenga
  • Transgenic, cross-linked hemoglobin
    Patent number: 5610137
    Abstract: Transgenic, recombinantly cross-linked polymeric human hemoglobins suitable as cell-free blood substitutes have been produced. A plurality of DNA constructs have been designed for efficient expression of modified human hemoglobins in the erythrocytes of the non-human transgenic animals. Substantially pure, non-immunogenic, artificial human hemoglobins are then easily obtained from the erythroid cells of the transgenic animals.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: March 11, 1997
    Assignee: The UAB Research Foundation
    Inventors: Tim M. Townes, Steven L. McCune