Abstract: The present invention is a peptide compound which stimulates the formation of hard tissues such as bone and cartilage. The invention is also related to a method to treat a defect in hard tissues such as bone and cartilage using the peptide. The method of the present invention may be used to treat or prevent the defects in bones and cartilages which are caused by rheumatoid arthritis or osteoarthritis which involves the regeneration of new bone or cartilage in or around the defects.
Type:
Grant
Filed:
January 22, 2008
Date of Patent:
February 15, 2011
Assignee:
Acologix, Inc.
Inventors:
Catherine Middleton-Hardie, Mirella Lazarov, David Rosen
Abstract: A controlled release formulation of lipoic acid is disclosed. The lipoic acid is combined with excipient materials in such a way that those materials protect the lipoic acid from chemical degradation in the gastrointestinal tract and provide for gradual release of the lipoic acid. These combined features make it possible to use lipoic acid to reduce serum glucose levels and maintain those levels over time thereby obtaining a range of desired results.
Abstract: A patient interface system for collecting and transferring data from a patient to a remote monitoring system, as well as methods for its use, are provided. The subject system uses: (a) a data collection device with a sensor and an interrogation device; (b) a processing device for processing the collected data; and (c) a communication device for transferring said collected data from the interface system to a remote monitoring system and receiving instructional data from a remote monitoring system. The subject system finds use in the remote monitoring of a variety of conditions, particularly in the remote monitoring of cardiac associated diseases. In addition, the sensor is a scale either programmed not to activate the patient interface system if it measures a weight below or above certain set weights or not to send measurements to the remote monitoring if it measures a weight below or above certain set weights.