Abstract: A method for making epothilones and epothilone analogs is described, as are novel compounds made by the method. Exemplary novel compounds include those according to the formula: With respect the formula, G is selected from the group consisting of R2 substituents independently are selected from the group consisting of H and lower alkyl groups; Z is selected from the group consisting of the halogens and —CN; M is selected from the group consisting of O and NR3; R3 is selected from the group consisting of H, lower alkyl, R4CO, R4OCO, and R4SO2; R4 is selected from the group consisting of H, lower alkyl, and aryl; T is selected from the group consisting of CH2, CO, HCOH and protected derivatives thereof; W is H or OR; and X and Y independently are selected from the group consisting of O, NH, S, CO, and C.

Abstract: A fish attractor made of transparent plastic has a triangular body having an aperture at the apex and one centrally located in the base, a substantially larger circular opening positioned centrally in the plane of transparent plastic, layers of holographic tape adhered to the sides of the attractor, the layers having circular openings therein corresponding in size to the opening in the transparent plastic, and a circular piece of plastic film larger in diameter than the circular openings in the layers of holographic tape and adhered to one of the layers of holographic tape such that the piece of plastic film is sandwiched between the plane of transparent plastic and the one layer of holographic tape, the piece of plastic film being stretched to provide a dome that vibrates and produces noise as the attractor moves through water.

Abstract: A new and distinct Heuchera plant characterized by rose colored flowers in a wand-type inflorescence, small yellow to lime colored leaves, very free flowering on short flower stalks, repeat blooming, and a well branched, small, mounding habit.