Patents Represented by Attorney Kathryn A. Lutomski

Find this attorney in the Justia Lawyer Directory

  • Composition and use
    Patent number: 8236345
    Abstract: A pharmaceutical composition, comprising a thiazolidinedione, such as Compound (I), metformin hydrochloride and a pharmaceutically acceptable carrier, wherein the thiazolidinedione and metformin hydrochloride are each dispersed within its own pharmaceutically acceptable carrier in the pharmaceutical composition and the use of such a composition in medicine.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: August 7, 2012
    Assignee: SmithKline Beecham Limited
    Inventors: Karen Lewis, Nicola Jayne Lilliott, Donald Colin MacKenzie
  • Quinoline derivatives and their use as 5-HTligands
    Patent number: 8236947
    Abstract: Disclosed are quinoline compounds having affinity for the 5-HT6 receptor and having the formula: where R1, R2, R3, R4, R5, n, m, p and A are defined herein, and salts thereof, compositions containing these compounds and salts and processes for making and using the same.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 7, 2012
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James MacDonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • Process for preparing piper azine derivatives
    Patent number: 8236953
    Abstract: The invention relates to compounds of formula (I): processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of conditions or disorders which are mediated via the GPR38 receptor.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: August 7, 2012
    Assignee: Glaxo Group Limited
    Inventors: Jonathan Thomas Seal, Geoffrey Stemp, Mervyn Thompson, Susan Marie Westaway
  • Compound, corresponding compositions, preparation and/or treatment methods
    Patent number: 8158645
    Abstract: Disclosed is a novel crystalline form of topotecan monohydrochloride pentahydrate, which is a pentahydrate of 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3?,4?:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione monohydrochloride, corresponding pharmaceutical compositions, methods preparation and/or use thereof to treat anti-viral and/or cancer-related diseases.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: April 17, 2012
    Assignee: GlaxoSmithKline LLC
    Inventors: Philip C. Dell'Orco, Ann Marie Diederich, Qiaogong Su, Jeffery Lee Wood
  • Heteroaryl derivatives of N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-amine
    Patent number: 8133908
    Abstract: Disclosed are N-{[(1S,4S,6S)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives having the following formula: wherein m, n, Het, R1, R2 and R3 are as defined herein, and their use as orexin antagonists.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: March 13, 2012
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Emiliano Castiglioni, Romano Di Fabio, Francesca Pavone
  • Imidazo[1,2-a]pyrazines as orexin receptor antagonists
    Patent number: 8129384
    Abstract: This invention relates to imidazopyrazine substituted piperidine derivatives and their use as pharmaceuticals.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: March 6, 2012
    Assignee: Glaxo Group Limited
    Inventors: Giuseppe Alvaro, David Amantini, Sandro Belvedere