Abstract: An improved process for preparing arylethanoldiamines is described. Compounds of this type are known to be useful as agonists at atypical beta-adrenoceptors (also known as beta-3-adrenoceptors).
Type:
Grant
Filed:
August 12, 2008
Date of Patent:
May 4, 2010
Assignee:
GlaxoSmithKline LLC
Inventors:
Jason William Beames Cooke, Bobby Neal Glover, Ronnie Maxwell Lawrence, Matthew Jude Sharp, Maria Fumiko Tymoschenko
Abstract: Heteroaromatic compounds are described, methods for their preparation, pharmaceutical compositions containing them, methods of use, and their use in medicines. In particular, the invention relates to quinazoline and pyridopyrimidine derivatives which exhibit protein tyrosine kinase inhibition.
Type:
Grant
Filed:
August 1, 2007
Date of Patent:
March 24, 2009
Assignee:
SmithKline Beecham Corporation
Inventors:
George Stuart Cockerill, Karen Elizabeth Lackey