Abstract: Novel pyrrole derivatives are disclosed as A?42-lowering agents for the treatment and prevention of neurodegenerative disorders characterized by the formation or accumulation of amyloid plaques comprising the A?42 peptide.
Type:
Grant
Filed:
May 6, 2010
Date of Patent:
July 10, 2012
Assignee:
Myrexis, Inc.
Inventors:
Warren S. Weiner, Rachel M. Slade, Yevgeniya I. Klimova, Ruth J. Walton, Mark B. Anderson