Patents Represented by Attorney Kelly Bender

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  • Milling process for the production of finely milled medicinal substances
    Patent number: 7041318
    Abstract: The present invention is a method of milling materials to form a fine powder with a median particle size below 10 micrometer which is suitable for inhalation and which has substantially no amorphous content generated during milling. The method is particularly suitable for milling materials which are soft. The method comprises milling the material in a fluid energy mill at reduced temperature using helium, or helium mixed with another gas, as milling fluid. Temperatures of ?30° C. or less are used.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: May 9, 2006
    Assignee: Aventis Pharma Limited
    Inventors: Jean-Rene Authelin, Patrick Hosek
  • 2-pyridinyl-6,7,8,9-tetrahydropyrimido{1,2-a}pyrimidin-4-one and 7-pyridinyl-2,3-dihydoimidazo{1,2-a}pyrimidin-5(1H)one derivatives
    Patent number: 6974819
    Abstract: Imidazo[1,2-?]pyrimidinones and pyrimido[1,2-?]pyrimidinones useful for preventive and/or therapeutic treatment of neurodegenerative diseases, such as Alzheimer's disease, caused by abnormal GSK3? activity.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: December 13, 2005
    Assignees: Sanofi-Aventis, Mitsubishi Pharma Corporation
    Inventors: Antonio Almario Garcia, Thierry Gallet, Adrien Tak Li, Alistair Lochead, Séverine Marguerie, Alain Nedelec, Mourad Saady, Philippe Yaiche
  • Pyrazolecarboxylic acid tricyclic derivatives, preparation and pharmaceutical compositions containing same
    Patent number: 6906080
    Abstract: The subject of the invention is tricyclic derivatives of pyrazolecarboxylic acid of formula: in which R1 represents a C3-C15 carboxyl radical or an NR2R3 group. The invention also relates to the method for preparing the compounds of formula (I), pharmaceutical compositions containing them. The compounds of formula (I) are active on cannabinoid CB1 receptors.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: June 14, 2005
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Serge Martinez, Murielle Rinaldi