Patents Represented by Attorney, Agent or Law Firm Kevin J. Forrestal
  • Stabilized compositions comprising a therapeutically active agent, and an oxidizing preservative
    Patent number: 8343949
    Abstract: Citric acid and conjugate bases thereof are useful for stabilizing stabilized chlorine dioxide in the presence of therapeutically active agents and excipients in a composition. Ophthalmic compositions and methods related thereto are also disclosed herein.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: January 1, 2013
    Assignee: Allergan, Inc.
    Inventors: Robert T. Lyons, Robert S. Jordan
  • Therapeutic compounds
    Patent number: 8338637
    Abstract: Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: December 25, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutically active cyclopentanes
    Patent number: 8299068
    Abstract: Disclosed herein are compounds having a formula: Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: October 30, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 8278347
    Abstract: A compound having a structure is disclosed herein. Compositions, medicaments, and therapeutic methods related thereto are also disclosed.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: October 2, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Therapeutic compounds
    Patent number: 8263593
    Abstract: Compounds comprising formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein J, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed, for treating baldness, glaucoma or inflammatory bowel diseases.
    Type: Grant
    Filed: April 21, 2009
    Date of Patent: September 11, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen
  • Substituted beta-lactams
    Patent number: 8202855
    Abstract: Disclosed herein is a compound comprising a formula or a pharmaceutically acceptable salt or a prodrug or a metabolite thereof; Y is A is —(CH2)6—, cis —CH2CH?CH—(CH2)3—, or —CH2C?C—(CH2)3—, wherein 1 or 2 carbon atoms may be substituted with S or O; or A is —(CH2)m—Ar—(CH2)o— wherein Ar is interarylene or heterointerarylene, the sum of m and o is from 1 to 4, and wherein one CH2 may be substituted with S or O; and D is aryl or heteroaryl. Methods of use are also disclosed.
    Type: Grant
    Filed: March 2, 2009
    Date of Patent: June 19, 2012
    Assignee: Allergan, Inc
    Inventor: David W. Old
  • Therapeutic amides
    Patent number: 8198318
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein G, E, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: June 12, 2012
    Assignee: Allergen, Inc.
    Inventors: David W. Old, Robert M. Burk, Todd Gac
  • Therapeutic substituted cyclic lactams
    Patent number: 8198315
    Abstract: Disclosed and described herein is a compound having a formula (I) therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: June 12, 2012
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic compounds
    Patent number: 8193373
    Abstract: Compound having the formula below are disclosed herein: formula (I). Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: June 5, 2012
    Assignee: Allergan, Inc.
    Inventors: Mark Holoboski, Robert M. Burk, Mari Posner
  • Cyclopentane heptan(ENE)OIC acid, 2-heteroarylalkenyl derivatives as therapeutic agents
    Patent number: 8168680
    Abstract: A compound comprising or a pharmaceutically acceptable salt or a prodrug thereof, having the groups described in detail herein is disclosed. Also disclosed herein are compounds comprising or derivatives thereof, or pharmaceutically acceptable salts, tetrazoles, or prodrugs of compounds of the structure or derivatives thereof, said derivatives being described in detail herein. Also disclosed herein are methods of treating diseases or conditions, including glaucoma and elevated intraocular pressure. Compositions and methods of manufacturing medicaments related thereto are also disclosed.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: May 1, 2012
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Robert M. Burk, Michael E. Garst
  • Substituted cyclopentanes having prostaglandin activity
    Patent number: 8158676
    Abstract: Disclosed herein are compounds having a formula: Therapeutic methods, medicaments, and compositions related thereto are also disclosed.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: April 17, 2012
    Assignee: Allergan, Inc.
    Inventor: Robert M. Burk
  • Therapeutic lactams
    Patent number: 8124648
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, J2, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: February 28, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Robert M. Burk
  • Therapeutic N-aryl or N-heteroaryl pyrazolidine and pyrazolidinone derivatives
    Patent number: 8093282
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J1, U1, U2, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: January 10, 2012
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Danny T. Dinh
  • Therapeutic compounds
    Patent number: 8003680
    Abstract: Disclosed herein are compounds of the formula therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: August 23, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Therapeutic substituted thiazolidinones, oxazolidinones, and related compounds
    Patent number: 8003678
    Abstract: A compound having a structure is disclosed herein. Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: August 23, 2011
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic substituted piperidone compounds
    Patent number: 7994195
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof are disclosed herein. Details are provided herein. Compositions, methods, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: August 9, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Robert M. Burk
  • Therapeutic substituted pyrroles
    Patent number: 7985765
    Abstract: Disclosed herein is a compound represented by a formula: Therapeutic methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: July 26, 2011
    Assignee: Allergan, Inc.
    Inventor: David W. Old
  • Therapeutic compounds
    Patent number: 7981887
    Abstract: Compounds comprising Formula (I) or a pharmaceutically acceptable salt thereof, are disclosed, wherein J1, J2, U1, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed, for treating glaucoma, inflammatory bowel disease and baldness.
    Type: Grant
    Filed: May 4, 2009
    Date of Patent: July 19, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Vinh X. Ngo
  • Substituted gamma lactams as therapeutic agents
    Patent number: 7973071
    Abstract: A compound comprising or a pharmaceutically acceptable salt, prodrug, or a metabolite thereof is disclosed herein. Y, A, and B are as described herein. Methods, compositions, and medicaments related to these compounds are also disclosed.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: July 5, 2011
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Danny T. Dinh
  • Therapeutic compounds
    Patent number: 7964599
    Abstract: Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein J, B, Y, and A are as described. Methods, compositions, and medicaments related thereto are also disclosed.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: June 21, 2011
    Assignee: Allergan, Inc.
    Inventors: Yariv Donde, Jeremiah H. Nguyen