Abstract: This invention provides compounds of Formula I having the structure and X are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.

Abstract: This invention provides compounds of Formula I having the structure and X are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.

Abstract: The invention relates to cosmetic and pharmaceutical creams in the form of an oil-in-water emulsion containing at least one polar oil as the oil component, said polar oil having an interfacial tension (&ggr;1) with water of less than 30 mN/m at 25° C., and at least one plant protein as the emulsifier, a 1 wt % aqueous solution of said plant protein having an interfacial tension (&ggr;2) with the oil component at 25° C. which is less than the interfacial tension &ggr;1 between oil and water. Protein or protein-containing meals consisting of oats, wheat or peas are preferred as emulsifiers, whilst the oil components preferably belong to the group of C8-C22 fatty acid esters of monovalent or polyvalent C2-C22 alkanol esters of monovalent or polyvalent C2-C6 hydroxycarboxylic acids.

Abstract: Oxidation colorants for coloring keratinous fibers comprising a primary intermediate and a secondary intermediate, wherein the primary intermediate comprises: a) a pyrimidine derivative wherein the pyrimidine ring is substituted with two to four amino groups and zero to two hydroxy groups; and b) 1-(2′-hydroxyethyl)-2,5-diaminobenzene or 2-(2′-hydroxyethylamino) -5-aminotoluene.

Abstract: A foaming aqueous body-cleansing composition of (a) an anionic surfactant, (b) an alkyl (oligo)glycoside, (c) a zwitterionic surfactant, (d) an ampholytic surfactant is presented. The body cleansing composition produces a stable, fine-bubble, creamy-feeling foam.

Abstract: The present invention relates to a skin lightening composition comprising (a) a safe and effective amount of a compound of formula (I): wherein Z is Oxygen or Sulfur, (b) an average polarity solvent, (c) a polyhydric alcohol, (d) a solid fatty alcohol, (e) a nonionic surfactant, (f) water, and (g) lecithin wherein at least a portion of the above components (a), (b), (c), (d), (e), (f) and (g) forms a liquid crystal.

Abstract: A molded synthetic composition is presented having at least 25% by weight synthetic surfactants, at least 30% by weight non-surface-active organic plasticizers and fillers, and 5 to 30% by weight of talcum. The composition provides improved moldability and initial foam quality.

Abstract: The invention relates to the utilization of onium aldehydes and onium ketones of formula (1) or the derivatives thereof. In the formula, R1 represents a hydrogen atom, a (C1-C4)-alkyl group, an aryl group or a heteroaryl group. R2, R3, R4, independent of one another, each represent a hydrogen atom, a halogen atom, a (C1-C4)-alkyl group, a (C1-C4)-alkoxyl group, hydroxy-(C1-C4)-alkoxyl group, hydroxyl group, nitro group, aryl group, trifluoromethyl group, amino group or (C1-C4)-acyl group. Said amino group can be substituted by (C1-C4)-alkyl groups. Two of the residuals can be combined to form a fused benzene ring. R5 represents a (C1-C4)-alkyl group, aryl group, alkylaryl group or heteroaryl group.

Abstract: Formulations for coloring keratinous fibers are provided, comprising a substantive dye, an aminopolycarboxylic acid or salt thereof with a physiologically compatible cation, and isoascorbic acid or a salt thereof with a physiologically compatible cation. Also provided are methods of coloring keratinous fibers with the formulations.

Abstract: The invention relates to lipid soluble, water insoluble cosmetic or dermatological active substances which can be included in body cleansing agents in the form of an aqueous preparation with at least 5 wt. % water soluble ionic or non-ionic surfactant content by solubilization of the active substances with a polar lipid in lipid-surfactant mixed micelles or liquid crystals or by microemulsification with a nonpolar lipid, wherein the emulsion particles have a diameter which is less than 500 nm. Said agents are also characterized by enhanced skin penetration by the active substances.

Abstract: Oxidation dyes that contain a developer-coupler combination of 2-(2,5-diaminophenyl)-ethanol or its salt with an organic or inorganic acid and 2-chloro-6-methyl-3-aminophenol or its salt with an organic or inorganic acid are characterized by intensive blue finishes with high rubbing fastness.

Abstract: A shaped soap composition is presented having 60 to 85 percent of an alkali metal soap of linear C12-22 fatty acid, 1 to 10 percent alkyl oligoglycoside and 5 to 20 percent talcum. The shaped soap as a smooth surface and exhibits improved washing properties and lime soap dispersion power.

Abstract: A colorant composition for coloring keratin-containing fibers is disclosed having (a) at least one isatin derivative corresponding to the formula I: where R1 and R2 independently of one another represent a hydrogen atom, a halogen atom, a hydroxy group, a (C1-4)-alkyl, hydroxy-(C1-4)-alkyl, tertiary amino-(C1-4)-alkyl, (C1-4)-alkoxy group, an amino group optionally substituted by one or two (C1-4)-alkyl or hydroxy-(C1-4)-alkyl groups, a nitro, carboxy, or sulfo group, and Y is a hydroxy group, a (C1-4)-alkoxy group or an amino group which may be substituted by (C1-4)-alkyl, (C1-4)-alkoxy-(C1-4)-alkyl, carboxy-(C1-4)-alkyl, sulfo-(C1-4)-alkyl or hydroxy-(C1-4)-alkyl groups or which may be part of a heterocyclic 5-, 6- or 7-membered ring, or physiologically compatible salts thereof, and (b) at least one compound containing a primary or secondary amino group or hydroxy group selected from the group consisting of primary or secondary aliphatic or aromatic amines, nitrogen-containing heterocyclic

Abstract: A 1,4-diazacycloheptane derivative and an oxidative hair colorant containing the derivative as a primary intermediate is presented. The 1,4-diazacycloheptane derivative is of the formula: ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently of one another represent hydrogen, a C.sub.1-4 alkyl or hydroxyalkyl group or a C.sub.2-4, dihydroxyalkyl group, X and Y independently of one another represent hydrogen, chlorine, fluorine, a C.sub.1-4 alkyl, hydroxyalkyl, aminoakyl or alkoxy group, a C.sub.2-4 dihydroxyalkyl group or an allyl group and R.sup.5 and R.sup.6 independently of one another represent hydrogen or a C.sub.1-4 alkyl group. Natural color tones can be obtained in keratin fibers with oxidative hair colorants containing the 1,4-diazacycloheptane derivative, without the use of additional primary intermediates.

Abstract: The present invention provides an aqueous nail coating composition containing a dispersion of multi-phase polymers. The aqueous nail coating composition has improved resistance to abrasion and chemicals.

Abstract: The present invention provides a composition useful in a washing process containing at least one vinyl amide polymer. The vinyl amide polymer contains from 5 to 100 weight percent of at least one vinyl amide monomer, and from 0 to 95 weight percent of one or more vinyl ester monomers. The present invention also provides a method of cleaning an article and a method of providing soil resistance to an article using the vinyl amide polymer.

Abstract: The present invention provides a fabric washing composition and aqueous treatment solution for inhibiting dye from transferring from one fabric to the same or different fabric in a fabric washing process. The fabric washing composition and aqueous treatment solution contain at least one dye deposition inhibiting polymer. The dye deposition inhibiting polymer contains, as polymerized units, from 5 to 100 weight percent of at least one vinyl amide monomer and from 0 to 95 weight percent of one or more vinyl ester monomers. The present invention also provides a method for inhibiting the deposition of dye by adding at least one of dye deposition inhibiting polymer useful in the present invention to a fabric washing process where dye may be released.

Abstract: A method is disclosed for improving the UV radiation absorption of a composition containing a UV radiation absorbing agent by adding from about 0.1 weight percent to about 50 weight percent of latex particles, based on total weight nonvolatiles. The latex particles contain a void and have a particle size of from about 100 nm to about 380 nm.

Abstract: The present invention provides aqueous low (70 weight percent or less) VOC hair styling compositions.More particularly, the present invention provides a low VOC hair styling composition containing at least one acrylic hair fixative resin and one or more plasticizing compounds selected from polycarboxylic acid esters and dimethiconecopolyols.The present invention also provides a low beading, low VOC hair styling composition comprising at least one surface tension reducing compound, at least one acrylic hair fixative resin, and at least one simethicone.The present invention also provides an aqueous hair resin composition which inhibits microbial growth. The aqueous hair resin composition contains at least one acrylic hair fixative resin and iodopropynylbutylcarbamate.