Patents Represented by Attorney, Agent or Law Firm Kirby W. Lee
  • Methods and compounds for inhibiting MRP1
    Patent number: 6686376
    Abstract: The present invention further relates to a method of inhibiting MRP1 in a mammal which comprises administering to a mammal in need thereof an effective amount of a compound of formula (I).
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: February 3, 2004
    Assignee: Eli Lilly and Company
    Inventors: Rosanne Bonjouklian, Jeremy Schulenburg York
  • Tricyclic compounds as MRP1-inhibitors
    Patent number: 6673809
    Abstract: The present invention relates to a compounds of formula I, wherein A is olefin, diol, or acetonide; which are useful for inhibiting resistant neoplasms where the resistance is conferred in part or in total by MRP1.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: January 6, 2004
    Assignee: Eli Lilly and Company
    Inventors: Peter Ambrose Lander, Qiuping Wang, Sreenivasarao Vepachedu
  • Methods for inhibiting MRP1
    Patent number: 6417193
    Abstract: The present invention relates to a compound of formula (I) which is useful for inhibiting resistant neoplasms where the resistance is conferred in part or in total by MRP1.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: July 9, 2002
    Assignee: Eli Lilly and Company
    Inventors: Joseph M Gruber, Bryan H Norman
  • Methods for inhibiting mrp1
    Patent number: 6369070
    Abstract: The present invention relates to a compound of formula (I), which is useful for inhibiting resistant neoplasms where the resistance is conferred in part or in total by MRP1.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: April 9, 2002
    Assignee: Eli Lilly and Company
    Inventors: Joseph M. Gruber, Julian S Kroin, Bryan H Norman