Abstract: A multichannel wireless telemetry system is disclosed. The system includes a transmitter and a receiver in communication with the transmitter. The transmitter includes a signal processing chip. The signal processing chip includes a plurality of input preamplifiers, a plurality of selective second amplifiers, a subcarrier oscillator connected to the selective second amplifiers, a timing circuit connected to the subcarrier oscillator, a calibration circuit connected to the timing circuit, and a 1-of-several decoder connected to the timing circuit. Each selective second amplifier is connected to a different input preamplifier.

Abstract: The invention is directed towards cutting inserts having a top surface, a bottom surface, at least three side surfaces extending from the top surface to the bottom surface, and a nose corner connecting two adjacent side surfaces. The intersection of the cutting insert may include an intersection of the nose corner and the top surface wherein at least a portion of the intersection defined by a multi-segment spline curve. The multi-segment spline curve may be a B-spline curve. The intersection may also be defined by two arcs at each end of the B-spline curve. The invention also includes a method of designing a turning insert having the steps of designing a nose corner with multi-segment spline curve. The multi-segment spline curve may be a B-spline curve.

Abstract: An improved system of resins comprising a combination of a sulfate-specific strongly basic anion exchange resin and a heterogenous hybrid thermally regenerable salt sorbent (TRSS) resin is provided. The anion exchange resin contains triethylamine and/or tributylamine groups. The TRSS resin comprises a macroporous host copolymer and a crosslinked guest copolymer having, respectively, weak acid groups and weak base groups. The system is used to treat feed water containing dissolved ions, including sulfate ions, and is efficiently regenerated.

Abstract: A delivery system for implanting medical devices within a lumen or body cavity of a patient, the delivery system having a wire formed from a plurality of layered strands yielding a reduced bending stiffness for improved maneuverability with no reduction in overall tensile strength compared to delivery systems using a single wire and of comparable diameter. The physical properties of the delivery system permit optimal placement and retrieval of an intracardiac occluder within a patient.

Abstract: A cutting insert for milling operations, such as, face milling, slot milling, plunge milling, and ramping operations. The cutting insert exhibits a combination of favorable cutting edge strength, and unique cutting edge geometry, thus, allowing milling operations at relatively high feed rates. The cutting insert includes at least four cutting edges, wherein at least one of the cutting edges is a convex cutting edge. Certain embodiments of square cutting inserts will have four convex cutting edges which may be connected by nose corners. The convex cutting edge may comprise at least one of a circular arc, a portion of an ellipse, a portion of a parabola, a multi-segment spline curve, a straight line, or combinations of these. Wherein the convex cutting edge comprises a circular arc, the circular arc may have a radius greater than or equal to two times a radius of the largest circle that may be inscribed on the top surface.

Abstract: Compositions, novel isolation sources and processes, and uses for unique policosanol containing compositions are disclosed. Seed and vegetable processing byproduct and/or “waste” streams are disclosed as containing policosanols with various relative amounts of the various long chain fatty/waxy alcohols. The policosanols are isolated and may be combined with other phytochemical/processing products, and are used in numerous food, beverage, health and/or nutraceutical applications.

Abstract: The present invention relates to a mounting adapter for releasably securing accessories, tools, or their medical instruments to the distal end of an endoscope. The adapter is compatible with endoscopic accessories that have a cylindrical mounting surface, which becomes positioned over a length of the distal end of an endoscope. The adaptor is preferably provided in two components to support both ends of a cylindrical accessory on the endoscope surface. The adapter is configured to hold the accessory on the endoscope shaft by frictional engagement and is configured to maintain the accessory concentric with the shaft along its length. The adapter also is configured to mount an accessory to a wide range of commercially available endoscope diameters.

Abstract: A device and method for monitoring a subject and providing feedback back to the subject that is pertinent to a behavior of the subject. The device includes a source of light having first and second wavelengths wherein the first wavelength does not equal the second wavelength; at least one image sensor producing a first signal indicative of reflected light having the first wavelength and a second signal indicative of reflected light having the second wavelength; a controller receiving the first and second signals and producing a third signal indicative of the first signal subtracted from the second signal; and an interface in communication with the controller providing informational content to the subject in response to the third signal, wherein the informational content is associated with a behavior of the subject.

Abstract: The invention generally relates to double-sided labels and methods of manufacture and use. More specifically, the invention relates to labels that include printed information on their front and back sides. The labels also include a detachable portion, which includes printed traces on its back side and is located between two portions of the label that contain adhesive on their back sides that permanently attach those portions to a product.

Abstract: Apparatus and methods for supporting conduits within a sanitary environment. Some supports are configured so as to avoid the formation of surfaces that might collect dust, debris, cleaning fluids, etc. when installed. In one embodiment, the support includes a pair of opposing support members that may be releasably and sealingly secured together. The upper support member may have a substantially uninterrupted convex surface that has a desired texture. The lower support member may be sized and shaped such that no portion thereof protrudes outwardly beyond the upper member to form any surfaces, pockets, etc. wherein dirt, debris, cleaning fluids, etc. may accumulate. A seal or grommet may be employed to establish a seal between the conduit and support to prevent the infiltration of dirt, debris, cleaning fluids, etc., between the conduit and the conduit support.

Abstract: The invention relates to compositions suitable for plasma substitution comprising as a plasma expander a recombinant gelatin-like protein. Characteristic is that the gelatin-like protein can be a monomer or a polymer like a dimer, trimer or a tetramer of a human recombinant gelatin-like protein having an isolectric point of less than 8. The resulting gelatin-like proteins provide a method to control the clearance rate of a plasma expander by its molecular weight. Preferably the gelatin-like proteins have a low hydroxyproline content which prevents the composition from gelling and thus allows the use of high-molecular weight proteins in order to establish a suitable colloid osmotic pressure. An additional advantage of the gelatin-like proteins is that these avoid the risk of anaphylactic shock that exists in conjunction with the use of commercially available preparations.

Abstract: The invention provides cytokine fusion proteins with an increased therapeutic index, and methods to increase the therapeutic index of such fusion proteins. The fusion proteins of the invention are able to bind to more than one type of cytokine receptor expressed on cells and also bind to more than one cell type. In addition, the fusion proteins of the invention exhibit a longer circulating half-life in a patient's body than the corresponding naturally occurring cytokine.

Abstract: Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.

Abstract: The invention provides devices and methods for identification of an epidural space. The invention also provides for visually determining when a needle enters the epidural space.

Abstract: The invention provides a wireless, internet-based system for monitoring and analyzing both GPS and diagnostic data collected from a vehicle. Specifically, the present invention provides a system for collecting these types of data and analyzing them to provide improved determination and mapping of the vehicle's location.

Abstract: The present invention provides a synthetic fiber and methods for its use and formation. The present invention may comprise a fiber component that is a twisted bundle comprised of multiple strands of a nonfibrillating monofilament, the degree of twist being greater than about 0.9 turns/inch (about 0.36 turns/cm). The present invention may further comprise another fiber component, discrete from the twisted fiber component, that is fibrillated.

Abstract: The invention provides a family of antibodies that specifically bind the human cell surface glycosphingolipid GD2. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies may be coupled to a therapeutic agent and used in the treatment of cancer.

Abstract: A method and a plant for simultaneous production of a gas for injection into an oil field and production of methanol, dimethyl ether and/or other oxygenated hydrocarbons or production of higher hydrocarbons from natural gas is disclosed. An air separation unit (ATR) for production of pure nitrogen for injection and pure oxygen for production of synthesis gas (“syngas”) by authermal reformation of a natural gas is an essential part of the method and plant.

Abstract: A support structure such as, for example, a door jamb and a window jamb. In one embodiment, the jamb is formed from a first stud that has a web and two first flanges and a second stud with a second web and second flanges. The first stud has at least one first hole through the first web and the second stud has at least one second hole through the second web. The first and second studs are oriented such that at least one first hole is aligned with at least one second hole and a stud engager is inserted through the aligned holes to retain the studs in abutting contact to form the jamb.

Abstract: Methods are disclosed for determining, in a sample derived from a human, the functional activity of a component of the human blood coagulation system, which activity can be correlated to conversion of a substrate specific for activated Protein C (APC), by measuring in an assay medium containing the sample and a substrate for APC, the conversion of the substrate by APC and correlating the conversion to the functional activity of the component. When the component is anticoagulant Factor V, at least one of exogenous APC, Protein S or an inhibitor of Protein S activity is added to the medium. When the component is Protein C, APC, or Protein S, exogenous anticoagulant Factor V or an inhibitor of anticoagulant activity of Factor V is added to the medium. Methods are also disclosed for diagnosing a blood coagulation/anticoagulation disorder or for determining a predisposition thereto in a human by determining anticoagulant Factor V activity in an assay medium containing a sample derived from the human.