Abstract: 12-(S)-hydroxyeicosapentaenoic acid is chemically extracted from the red alga Murrayella periclados. Fresh or frozen quantities of Murrayella periclados are first macerated and combined with a 2:1 mixture of chloroform and methanol. This results in an organic fraction containing lipid isolates. After filtration to remove extraneous solids, the organic fraction is evaporated to produce a tar. The tar contains 12-(S)-HEPE which is further purified as desired.
Type:
Grant
Filed:
October 9, 1987
Date of Patent:
March 7, 1989
Assignee:
The State of Oregon Acting by and through the Oregon State Board of Higher Education on Behalf of Oregon State University