Abstract: A polymer-drug conjugate, in which the polymer is the polysaccharide dextrin, linked directly or indirectly to the drug, is effective to deliver the drug to a target site and is biodegradable. The conjugate may be prepared by succinoylating dextrin followed by reaction with the drug or a derivative thereof.
Type:
Grant
Filed:
March 23, 2000
Date of Patent:
January 15, 2002
Assignee:
ML Laboratories
Inventors:
Ruth Duncan, James Cassidy, Lisa German, Dale Hirst