Abstract: A pharmaceutical composition comprises M3 protein as encoded by virus MHV 68, or a homologue of said M3 protein, for use in binding to a chemokine or a chemokine analogue in vivo, or to block binding of chemokines to corresponding cell surface receptors in vivo, to produce an immunomodulatory effect, or to bind to a chemokine analogue present in a virus or parasite to block its entry into cells.
Type:
Grant
Filed:
July 17, 2000
Date of Patent:
January 18, 2005
Assignee:
Cambridge University Technical Services Limited
Inventors:
Stacey Efstathiou, Antonio Alcami, Christopher Marc Parry, Vincent Peter Smith, João Pedro Monteiro e Louro Machado de Simas