Abstract: Compounds represented by the following formula I:
in which:
R1 to R5 can have various meanings of which alkyl, substituted or non-substituted aryl, and m is equal to 0 or 1, X is selected from (CR6R7)n in which n=0 or 1, and CO are disclosed. These compounds are useful as anti-tumor drugs, especially with pro-oxidizing activity.
Type:
Grant
Filed:
August 28, 2000
Date of Patent:
June 18, 2002
Assignee:
Oxis International, Inc.
Inventors:
Jinzhu Xu, Georges Appere, Jean Chaudiere, Jean-Claude Yadan