Abstract: In a method for administering systemically active agents including therapeutic agents through the skin or other body membranes of humans and animals typically in the form of a transdermal device or formulation, the improvement comprising the use therewith of an effective amount of a membrane penetration enhancer having the structural formula. ##STR1## wherein R is H or a lower alkyl group, m is 5-7 and n is 0-17.

Abstract: A method of dielectrically joining the mated ends of tubular members is, specifically, used in the formation of a cannula for insertion into a body cavity, duct, or vessel of a patient. The cannula preferably includes a parent cannula member and an integrally joined tip. The method comprises the steps of joining the mated ends of the tubular members to form a common joint, passing a high frequency electrical current between the electrodes of a dielectric heating device and through the mated ends of the tubular members to heat and fuse them together at said joint, concentrating the heat at the joint to form an integral cannula, permitting the hot air surrounding the joint to escape in order to prevent the burning or scorching of said cannula, pressurizing the joint to facilitate the escape of the hot air and to eliminate dimensional differences in the mated ends, and forming the mated ends of the tubular members while in a heated condition to provide smooth surfaces on the cannula.

Abstract: Compounds are disclosed having the formula: ##STR1## wherein: R.sub.1 is H, OH, --OCH.sub.3, --CH.sub.2 OH, --NH.sub.2, --NHMe, --NHEt, --NMe.sub.2, --NEt.sub.2, ##STR2## R.sub.2 is H, --CH.sub.3, or ##STR3## R.sub.3 is phenyl, benzyl, or 1-4 carbon alkyl; R.sub.4 is H, --CH.sub.3, --CH.sub.2 OH, --CH.sub.2 --CN, --CH.sub.2 --S--Me, CH.sub.2 --S--CN, or ##STR4## R.sub.5 is H, 1-4 carbon alkyl, alkenyl, or alkynyl, or aralkyl having a 1-4 carbon alkylene moiety; and A is --CH.sub.2 --or --CH.sub.2 CH.sub.2 --, and pharmaceutically-acceptable salts thereof. Pharmaceutical preparations using these compounds and a method for inducing a dopaminergic response by administering these compounds are also disclosed.

Abstract: In the event of fire, a telescoping pole is transported, by means of a hoist, from a stored location within a building to a sleeve permanently mounted on a balcony or near a window. The pole is inserted into the sleeve and telescoped to its full extended position. A trolley is mounted on this pole. The user straps himself in a seat, attaches the seat to the trolley, and suspends himself from the pole. Using a hand-over-hand motion, the user propels himself away from the building to the end of the pole where he may be rescued by firemen.In a second embodiment, the pole is telescopingly mounted and permanently stored in the sleeve, thereby eliminating the need to transport the pole. The sleeve is pivotally mounted on a stand for rotation about a vertical axis and the pole, when stored therein, is interior to the side of the building. In the event of fire, the user manipulates the pole by rotating it to a position which permits it to be telescopingly extended away from the side of the building.

Abstract: A jet carrier assembly for cleaning well liners has a jet tool stabilized by a centralizer proximate to each of the tool's upper and lower ends. The jet tool is an elongate member having about 4 to 8 pairs of jet nozzles axially spaced therebetween, the axial spacing between alternate pairs being equal. The jet nozzles are spaced to provide a jet fluid track that covers any given point on the liner at least once but not more than twice when the member is lifted at a constant selected vertical speed and a constant selected rotational speed. The nozzles are mounted within adapters which are in turn detachably mounted to the elongate member. The adapters, which are provided in various sizes depending upon the diameter of the well liner, are interchangeable. The centralizers are capable of axial and rotational movement along mandrels attached to the upper and lower ends of the tool.

Abstract: A high frequency compression driver is disclosed in which the driver assembly is secured by two threaded studs. The studs not only hold the cover, magnet assembly and horn together, but also play a vital role in ensuring that the various elements of the assembly do not shift with respect to each other. The studs also serve as a basis for centering the voice coil precisely between the poles of the driver magnet. Although the magnet assembly is manufactured with ordinary machine tolerances, the diaphragm and voice coil are centered through the use of two precisely machined fixtures. The cover of the assembly acts as an effective heat sink for the diaphragm to keep its temperature low and improve the reliability of the device. The diaphragm itself is manufactured at low cost, is replaceable and is given structural integrity by the cover and the pole ring.

Abstract: A fully automated system for cleaning and disinfecting blood dialyzers is disclosed.

Abstract: An engine hoist with a hydraulically powered lifting boom is attached to and used in combination with an automobile hoist.