Abstract: Compounds, compositions and methods are provided for modulating the expression of Tudor-SN. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Tudor-SN. Methods of using these compounds for modulation of Tudor-SN expression and for diagnosis and treatment of diseases and conditions associated with expression of Tudor-SN are provided.
Type:
Grant
Filed:
May 23, 2005
Date of Patent:
July 21, 2009
Assignee:
Isis Pharmaceuticals, Inc.
Inventors:
Nicholas M. Dean, Ming-Yi Chiang, Kenneth W. Dobie