Patents Represented by Attorney, Agent or Law Firm Kolasch & Birch, LLP
  • Process for the preparation of prostaglandins
    Patent number: 6313341
    Abstract: A hydroxy-1-alkyne is reacted with a tin hydride compound, and the obtained (E,Z)-hydroxyvinylstannanes are separated to give the (E)-substance which is further converted to a vinylcopper complex shown by followed by the conjugate addition reaction with an &agr;, &bgr;-unsaturated cyclopentenone, and the deprotecting reaction is subsequently carried out to prepare a prostaglandin or an intermediate of prostaglandins easily, efficiently and industrially favorably.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: November 6, 2001
    Assignee: Fuji Yakuhin Kogyo Kabushiki Kaisha
    Inventors: Noriaki Murata, Atsunori Aramata, Tadashi Takeuchi