Abstract: Antibodies and fragments that bind to the protein target c-Met, particularly to epitopes located in the c-Met extracellular domain, are provided, as are methods of use of the antibodies and kits, for treating an unwanted cell, in particular, a cell associated with a c-Met-related condition such as a cancer, a metastasis, or an inflammatory condition.
Type:
Grant
Filed:
March 29, 2007
Date of Patent:
January 24, 2012
Assignee:
Novartis AG
Inventors:
David Raymond Stover, Josef Prassler, Catrin Berger, Bodo Brocks