Patents Represented by Attorney L. Eric Thies

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  • Phenylsulphonylipiperazinyl derivatives as 5-HT receptor ligands
    Patent number: 6852718
    Abstract: A class of phenylsulphonyl derivatives wherein the sulphonyl moiety is also attached to an N-arylalkyl-substituted piperazine ring are selective antagonists of the human 5-HT2A receptor and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of adverse conditions of the central nervous system, including schizophrenia and other psychotic disorders.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: February 8, 2005
    Assignee: Merck Sharp & Dohme Ltd
    Inventors: Frank Burkamp, Susan Koon-Fung Cheng, Stephen Robert Fletcher