Patents Represented by Attorney L. R. Hattan

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  • Autoxidation of alkyl-substituted aromatic ethers
    Patent number: 4526984
    Abstract: A method is described for autoxidizing ortho-dialkyl substituted aromatic ethers directly to their corresponding carboxylic acid anhydrides. The method comprises autoxidizing the ethers in a first step in a solution of an aliphatic monocarboxylic acid having 2 to 8 carbon atoms to form a partially oxidized reaction mixture. The autoxidation of the partially oxidized mixture is continued in a second step after the addition of an anhydride of an aliphatic monocarboxylic acid having 3 to 8 carbon atoms and at a temperature of at least 130.degree. C. to form said anhydrides.The anhydrides are used in the preparation of organic high temperature polymers such as polyamideimides, polyimides, polyetherimides, and polyetherimideamides.
    Type: Grant
    Filed: October 29, 1984
    Date of Patent: July 2, 1985
    Assignee: The Upjohn Company
    Inventor: Visweswara R. Durvasula
  • Methods for treating gastrointestinal inflammation
    Patent number: 4359465
    Abstract: The present invention relates to the novel cytoprotective use for known heterocyclyalkylsulfinylbenzimidazoles, and novel, substantially non-antisecretory unit dose pharmaceutical compositions thereof.
    Type: Grant
    Filed: July 28, 1980
    Date of Patent: November 16, 1982
    Assignee: The Upjohn Company
    Inventor: Mary J. Ruwart
  • 19-Hydroxy-6-oxo-PGF.sub.1 amides
    Patent number: 4312997
    Abstract: The present invention provides novel 19-hydroxy-6-oxo-PGF.sub.1 amides which are useful for pharmacological purposes, e.g., anti-asthmatic indications.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: January 26, 1982
    Assignee: The Upjohn Company
    Inventor: John C. Sih
  • Radioenzymatic assay of catecholamines
    Patent number: 4284587
    Abstract: A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.
    Type: Grant
    Filed: October 12, 1978
    Date of Patent: August 18, 1981
    Assignee: The Upjohn Company
    Inventors: Garland A. Johnson, Jacob D. Peuler
  • Method for separating gases
    Patent number: 4264338
    Abstract: An improved process for the separation of gases by selective membrane diffusion or permeation by means of plural stages of membrane separation without increasing the work required by directing a permeant mixture from a second or later stage of separation to a recycle stage of membrane separation to provide a permeate enriched in the desired gas or gases and blending said permeate with the gaseous feed to said second or later stage of separation.
    Type: Grant
    Filed: August 16, 1979
    Date of Patent: April 28, 1981
    Assignee: Monsanto Company
    Inventor: Harold R. Null
  • Enhancing zinc serum and tissue levels
    Patent number: 4124718
    Abstract: Zinc serum and tissue levels are enhanced by therapeutic administration of certain .alpha.-mercapto-.beta.-aryl acrylic acids.
    Type: Grant
    Filed: January 21, 1977
    Date of Patent: November 7, 1978
    Assignee: Merrell Toraude et Compagnie
    Inventors: Eugene L. Giroux, Nellikunja J. Prakash, Paul J. Schechter
  • Lactamimide inhibitors of gastrointestinal hypersecretion
    Patent number: 4061746
    Abstract: A method of treating gastrointestinal hypersecretions which comprises administering substituted lactamimide derivatives.
    Type: Grant
    Filed: April 23, 1976
    Date of Patent: December 6, 1977
    Assignee: Richardson-Merrell Inc.
    Inventors: Thomas R. Blohm, J. Martin Grisar, Norbert L. Wiech
  • Cephalosporin antibiotics
    Patent number: 4031083
    Abstract: Novel cephalosporin antibiotic derivatives.
    Type: Grant
    Filed: October 24, 1975
    Date of Patent: June 21, 1977
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Fortuna Haviv, Abraham Patchornik, Janina Altman