Abstract: A compound of the formula ##STR1## and intermediates useful in preparing same.

Abstract: A compound of the formula ##STR1## and intermediates useful in preparing same.

Abstract: The compound 6,9-deepoxy-6,9-(phenylimino)-.DELTA..sup.6,8 -prostaglandin I.sub.1, potassium salt and compositions thereof.

Abstract: Novel compounds of the following general formula: ##STR1##

Abstract: Immunoassays which utilize an enzyme linked ligand or receptor wherein the enzyme is bacterial luciferase; mercantile kit useful in performing said immunoassay; and compounds utilized in performing said assay.

Abstract: Novel compounds of the following general formula: ##STR1##

Abstract: Novel compounds of the following general formula: ##STR1##

Abstract: A compound of the formula ##STR1## wherein St represents a corticosteroid moiety bonded to the carbonyl via the21-hydroxy group of said corticosteroid;whereinZ is a bond or --O--;whereinn is an integer from 4 to 9;whereinQ is(1) Y--CH.sub.2 COOH wherein Y is --S--, --S(0)--, --S(0.sub.2)--, --SO.sub.2 N(R)--, or --N(R)SO.sub.2 ; R is hydrogen or lower alkyl(C.sub.1 -C.sub.4) with the proviso that the total carbon atoms in R and (CH.sub.2).sub.n is not greater than 10;(2) ##STR2## or (3) ##STR3## wherein R.sub.1 is hydrogen and R.sub.2 is H, CH.sub.3,CH.sub.2 COOH, CH.sub.2 CH.sub.2 COOH, CH.sub.2 OH, CH.sub.2 SH, CH.sub.2 CH.sub.2 SCH.sub.3, or CH.sub.2 Ph--(OH) wherein Ph is phenyl and Ph--(OH) is p-hydroxyphenyl; or R.sub.1 is CH.sub.3 and R.sub.2 is H; or R.sub.1 and R.sub.2 taken together are --CH.sub.2 CH.sub.2 CH.sub.2 --; or N(R.sub.1)CH(R.sub.2) COOH taken together is NHCH.sub.2 CONHCH.sub.2 COOH; and pharmaceutically salts thereof.

Abstract: Novel compounds of the following general formula: ##STR1##

Abstract: The present invention provides a novel means for the isolation of bacterial luciferase and a novel affinity resin useful in said isolation.

Abstract: An improved process for the reaction injection molding of high flexural modulus polyurea containing elastomers is disclosed. Elastomers of this type when prepared at the prior art molding temperatures are brittle and can shatter like glass while still in the mold. The same elastomers when molded at a temperature of from about 90.degree. to about 220.degree. C. are not at all brittle. These elastomers are also characterized by the other advantageous properties inherent in polyurea elastomers such as high tensile strength, high hardness, and good heat resistance.The improved RIM process finds particular utility in the preparation of auto parts such as panels, engine hoods, and the like.

Abstract: The compound 15-cyclohexyl-9-deoxy-13,14-dihydro-2',9.alpha.-methano-3-oxa-4,5,6,16,17, 18,19,20-octanor-3,7(1',3-interphenylene)PGF.sub.1 and pharmacologically acceptable salts thereof.

Abstract: Disclosed is a method for the trimerization of organic isocyanates comprising thermally activating, in the presence of said isocyanates, a catalyst comprising a carboxylic acid salt selected from the alkali metal salts or quaternary ammonium salts of particular substituted malonic acids or half-esters thereof, particular carbamyl substituted aliphatic acids, or triaryl acetic acids.Mixtures of the catalysts with isocyanates have surprisingly long periods of stability at ambient temperatures (about 20.degree. C.) which makes the present method particularly suitable to systems for molding polyiso-cyanurates wherein long open times are required of a resin pre-mix prior to the actual curing step.

Abstract: Disclosed are novel compositions capable of catalytically trimerizing organic isocyanates said compositions comprising solutions of the reaction products obtained by reacting in an inert solvent in substantially equimolar proportions electron-rich ketene-aminals with electron-poor olefins having the respective formulae (I) and (II) ##STR1## The variously substituted electron-rich ketene-aminals (I), as the name implies, have high electron density associated with the double bond because of the two tertiary amine groups while the electron-poor olefins (II) have the opposite situation due to the presence of electron withdrawing substituents R.sub.9 and R.sub.10.Also disclosed is an improved process for trimerizing organic isocyanates using the above catalyst compositions including the preparation of polyisocyanurate polymers and isocyanurate-modified polyisocyanates.

Abstract: Disclosed are injection moldable, rapidly crystallizable compositions comprising (A) a linear polyamide selected from the series poly(4,4'-methylenediphenylene azelamide to dodecanediamide); and (B) an amount sufficient to promote the crystallization of the linear polyamide, of a material selected from the group of (i) talc, (ii) sodium benzenesulfonate, (iii) a polyethylene ionomer, (iv) a methacrylated butadiene-styrene, and (v) a multi-phase composite interpolymer.The compositions crystallize rapidly from the molten state which allows for economically attractive molding procedures including fiber production and the production of aromatic-aliphatic polyamides having a combination of excellent properties.

Abstract: Novel compounds of the following general formula: ##STR1##

Abstract: The present specification provides novel analogs of carbacyclin (CBA.sub.2), 6a-carba-prostacyclin (6a-carba-PGI.sub.2), which have pronounced prostacyclin-like pharmacological activity, e.g., as platelet anti-aggregatory agents. Specifically the novel chemical analogs of CBA.sub.2 are those substituted by fluoro (C-5), alkyl (C-9), interphenylene (C-5), methano (C-6a,9), and an additional (olefinic) valence bond (C-6a,9). Further provided are benzindene analogs of CBA.sub.2 and substituted forms thereof, i.e., 9-deoxy-2', 9-methano (or 2', 9-methano)-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylene)-PGF.sub.1 compounds. Also provided are a variety of novel chemical intermediates, e.g., substituted bicyclo[3.3.0]octane intermediates, and chemical process utilizing such intermediates which are useful in the preparation of the novel CBA.sub.2 analogs.

Abstract: The present invention provides novel methods and compositions for treatment of pathological mineral resorptive states (PAMIRS), e.g., osteoporosis, employing disodiumchromoglycate (DSCG) and antiallergenic biologues, including other bis chromones, benzopyrans, and oxamates.

Abstract: Prostaglandin (PG.sub.1) derivatives having a 5,6-didehydro feature, for example an enol ether of the formula ##STR1## said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

Abstract: Novel antibacterially-active compound, 1,2,8,8a-cyclopropa[c]benzo[1,2-b:-4,3-b']dipyrol-4(5H)-one, prepared by a novel chemical process. This compound, as well as antibacterially-active intermediates, can be used to eradicate or control susceptible bacteria, for example, B. subtilis, K. pneumonia, S. lutea, S. aureus, and M. avium.