Abstract: Genetically engineered cells and animals are described that incorporate a mutated GHP1 allele. Animals that are homozygous for the mutated GHP1 allele are useful for the production of monoclonal antibodies against GHP1.
Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in thereapeutic, diagnostic, and pharmacogenomic applications.
Type:
Grant
Filed:
April 12, 2001
Date of Patent:
May 20, 2008
Assignee:
Lexicon Pharmaceuticals, Inc.
Inventors:
D. Wade Walke, Nathaniel L. Wilganowski, C. Alexander Turner, Jr.
Abstract: Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.
Type:
Grant
Filed:
December 29, 2004
Date of Patent:
May 20, 2008
Assignee:
Lexicon Pharmaceuticals, Inc.
Inventors:
D. Wade Walke, Erin Hilbun, Gregory Donoho, C. Alexander Turner, Jr., Gwenn Hansen, Hector BeltrandelRio, Isaac Van Sligtenhorst
Abstract: Polynucleotide and polypeptide sequences that encode novel variant FAM3C proteins are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.