Abstract: A vaccine effective against Marek's disease virus (MDV) comprises (a) an MDV attenuated by virtue of being TK- or (b) a host expressing an MDV antigen, namely the respective MDV homologues of the HSV gB, gC, gD or gH glycoproteins (or antigenic parts thereof) or the respective MDV homologues of the HSV-1 immediate early genes IE-68 or IE-175. The host may be a herpes virus of turkeys (HVT), more particularly HVT in which the MDV antigen is inserted in the HVT homologue of the HSV gC gene, the ribonucleotide reductase (large subunit) gene or the thymidine kinase (TK) gene.
Type:
Grant
Filed:
December 30, 1998
Date of Patent:
August 8, 2000
Assignee:
Merial
Inventors:
Louis Joseph Norman Ross, Simon David Scott, Matthew McKinley Binns
Abstract: 7-O-(4-Amino-2,4,6-trideoxy-2-fluoro-.alpha.-L-mannopyranosyl)-daunomycinon e or -adriamycinone is now synthesized as a daunomycinone or adriamycinone derivative having the general formula ##STR1## wherein R is a hydrogen atom or hydroxyl group. These novel compounds according to this invention exhibit excellent antitumor activities and have a high solubility in water, and hence they are useful as an antitumor agent.
Type:
Grant
Filed:
March 31, 1999
Date of Patent:
June 13, 2000
Assignee:
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
Abstract: A compact and highly effective dielectric duplexer comprises a dielectric ceramic block and a plurality of resonators arranged in a direction in the dielectric ceramic block, a half of the resonators constituting a transmitting section T, the remaining half of the resonators constituting a receiving section R, wherein an antenna terminal pad is capacitively coupled to the innermost resonator of the transmitting section T and to the innermost resonator of the receiving section R located adjacent to the innermost resonator to eliminate the use of a wave-dividing resonator, whereby the dielectric ceramic block can be dimensionally reduced in the direction along which resonators are arranged and hence it is adapted to down-sizing.
Abstract: Known cyclic depsipeptides which are PE 1022F substance and PF 1022H substance, as well as a novel cyclic depsipeptide, PF 1022G substance, are now prepared simultaneously by cultivating a fungal strain capable of producing PF 1022F substance, PF 1022G substance and PF 1022H substance represented by the known PE 1022 strain (deposited under FERM BP-2671) which is a kind of fungus belonging to asporous imperfect fungi (the order Agonomycetales) and is presumable to belong to the genus Xylaria or the genus Rosellinia in the family Xylariaceae.
Abstract: A rivet tool has a rivet pin which can be moved in a bore of a stamp die. The tool consists of a hydraulic cylinder having two pistons in which the first piston carries the rivet pin and the second piston carries the stamp die. The chamber between the pistons is connected with a variable volume pressure chamber. The cylinder chamber, which is facing the first piston, is connected with a pressure cylinder. After a rivet has been conveyed to beneath the rivet pin, a pressure cylinder is activated and a throttle interconnected between the chamber between the pistons and the pressure chamber. The stamping process is carried out hereby and the first piston is then pressed in direction of the second piston, whereby the first piston then lies on top of the second piston to effect the stamping process.
Abstract: This invention provides hexagonal crystals of a diacetal represented by the formula (1) ##STR1## wherein R.sup.1 and R.sup.2 each represents an alkyl group having 1 to 4 carbon, atoms or a halogen atom, each of m and n is an integer of 0 to 2 and p is 0 or 1, a nucleating agent comprising the diacetal of the formula (1), wherein part or the whole of the diacetal is in the form of hexagonal crystals, a polyolefin resin composition and a molded product each comprising a polyolefin resin and the nucleating agent, and a method for molding the polyolefin resin composition.According to the invention, the occurrence of fish eyes and coloration in a molded product can be prevented, the optical, mechanical and thermal properties of the molded product are superior and the molding cycle is shortened.