Patents Represented by Attorney, Agent or Law Firm Larson & Taylor PLC
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Patent number: 6818744Abstract: This invention relates to a new protein called RB18A for “Recognized By PAb18O1 moAntibody”, which is a p53 regulatory protein, to the nucleotide sequence encoding said protein, and to the diagnostic and therapeutic applications thereof, in particular for the diagnosis, prevention or treatment of neoplasia.Type: GrantFiled: August 14, 2000Date of Patent: November 16, 2004Inventor: Raymond Frade
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Patent number: 6743467Abstract: A method is provided for forming a modified gel capable of forming a hydrophobic surface on which water has a contact angle of at least 150°. Additionally, a method is provided for forming a hydrophobic coating from the modified gel. In some embodiments, the hydrophobic coating has an extremely high hydrophobicity with a contact angle in excess of 165°, and good substrate adhesion. The method involves bonding a gel with particulate matter. It is believed that the chemical hydrophobicity of the gel is enhanced by the physical roughness of the particulate matter.Type: GrantFiled: May 1, 2002Date of Patent: June 1, 2004Assignee: Unisearch LimitedInventors: Ashley Jones, Robert Norman Lamb, Hua Zhang
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Patent number: 6725975Abstract: In order to position a rotary actuator, a positioning device is coupled to the actuator. The positioning device has a coupling shaft and springs which respectively surround top and bottom portions of the shaft and are coupled thereto by respective coupling rings. The springs apply oppositely directed torques to the shaft such that one spring urges the shaft in a clockwise direction towards a stop position and the other spring urges the shaft in a anticlockwise direction towards that stop position. The stop position corresponds to an intermediate rotary position of the actuator.Type: GrantFiled: August 22, 2001Date of Patent: April 27, 2004Assignee: Kinetrol LimitedInventor: Roger C. Chapman
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Patent number: 6723578Abstract: Method for deoxidizing and passivating, by sulphidation, a surface of a III-V compound semiconductor material undergo strong oxidation in the presence of oxygen, wherein the surface to be passivated is immersed in a dilute aqueous solution containing sulphide ions with a concentration of between about 10−1M and 10−7M.Type: GrantFiled: May 30, 2002Date of Patent: April 20, 2004Assignee: Sagem SAInventors: Dominique Lorans, Bruno Canava, Arnaud Etcheberry, Michel Herlem, Jacky Vigneron
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Patent number: 6720949Abstract: Affordable methods and apparatus are disclosed for inputting position, attitude (orientation) or other object characteristic data to computers for the purpose of Computer Aided Design, Painting, Medicine, Teaching, Gaming, Toys, Simulations, Aids to the disabled, and internet or other experiences. Preferred embodiments of the invention utilize electro-optical sensors, and particularly TV Cameras, providing optically inputted data from specialized datum's on objects and/or natural features of objects. Objects can be both static and in motion, from which individual datum positions and movements can be derived, also with respect to other objects both fixed and moving. Real-time photogrammetry is preferably used to determine relationships of portions of one or more datums with respect to a plurality of cameras or a single camera processed by a conventional PC.Type: GrantFiled: August 21, 1998Date of Patent: April 13, 2004Inventors: Timothy R. Pryor, Peter Smith
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Patent number: 6718938Abstract: A rotary internal combustion engine comprises a four-segment hinged rotor assembly accommodated in a coaxial housing such that the rotor assembles deforms and continuously adapts to the housing internal profile during its rotation. The closed non-circular rotor housing internal profile is a curve defined by a novel mathematical relationship. The curve is the locus of all points generated by the base extremities A and B of an isosceles right angle translating and simultaneously rotating triangle with the following constraints. The center point P of the base AB (of length c) of the triangle must always be located on an inscribed circle of radius c/2 and center at point O. The vertex C of the triangle must always be located on one of the four lobes of the curve of the form r=sin(2&thgr;) where angle &thgr; is the angle between line OA and the positive vertical (y) axis and also line OB and the positive horizontal (x) axis.Type: GrantFiled: June 13, 2002Date of Patent: April 13, 2004Inventor: Peter Szorenyi
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Patent number: 6713261Abstract: The invention concerns a method for assessing in vitro the genotoxicity of a compound, which consist in contacting said compound with at least a cell or cell type overexpressing bcl2 protooncogene and/or related anti-apoptotic protein, and observing the genotoxic effects of said compound on said cell.Type: GrantFiled: August 7, 2002Date of Patent: March 30, 2004Assignees: Institut National de la Sante et de la Recherche Medicale, Institut Pasteur de LilleInventors: Marc Pallardy, Daniel Marzin, Sophie Meintieres, Armelle Biola
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Patent number: 6708720Abstract: A valve actuator adaptor attaches a rotary valve whose mounting is in accordance with ISO 5211/DIN 3337 to a rotary actuator whose mounting is not in accordance with ISO 5211/DIN 3337. The adaptor has first and second mounting surfaces to which the valve head and the actuator are respectively secured and a coupling link extends through the body of the adaptor to interconnect the actuator drive shaft and the valve stem. The adaptor has holes which extend from the first mounting surface to an exposed surface intermediate along the axial length of the actuator. That exposed surface is formed by recesses in the body of the actuator and by partial flanges. Screws or bolts then pass through those holes to the adapter to the valve head, the exposed surface having recesses therein, which recesses are shaped to receive the heads of the screws or bolts, or nuts on the bolts, to prevent them rotating.Type: GrantFiled: October 2, 2002Date of Patent: March 23, 2004Assignee: Kinetrol LimitedInventor: Roger C. Chapman
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Patent number: 6709101Abstract: The present invention provides an apparatus and method for avoiding ocular muscular fatigue, the apparatus comprising a binocular light converging means (12, 14) for converging incident light (18, 20), thereby reducing ocular convergence demand when the apparatus is worn by a user. In a preferred embodiment, the binocular light converging means comprises a pair of lenses.Type: GrantFiled: May 30, 2001Date of Patent: March 23, 2004Assignee: Positive Plan PTY LTDInventor: Henri Kwok-Wai Lee
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Patent number: 6706684Abstract: The invention concerns a method for preparing a non-toxic, sterile, biocompatible, crosslinked collagen material with controlled in vivo biodegradation speed. It consists in subjecting a collagen constituent, either to beta radiation, or to gamma radiation. The collagen material obtained is biodegradable in a few days depending on the type of irradiation used.Type: GrantFiled: May 29, 2001Date of Patent: March 16, 2004Assignee: Imedex BiomateriauxInventors: Yves Bayon, Philippe Gravagna, Jean-Louis Tayot
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Patent number: 6705382Abstract: The method of improving the mould quality of a mould-forming machine comprising at least one moulding chamber with oppositely positioned and movable squeeze plates, in which the mould-forming process comprises the steps of a) filling the at least one moulding chamber with compressible mould material, b) pressing the mould material between the squeeze plates, c) opening the moulding chambers(s) by moving at least one of the squeeze plates, d) removing the produced mould or mould parts from the moulding chamber(s) and e) reclosing the moulding chambers(s) by moving at least one of the squeeze plates, ready for a new cycle starting from step (a), by moving at least one squeeze plate in a direction reducing the volume of the moulding chambers(s) during at least part of the filling step a), an improved filling of mould cavities is achieved, which compensates for the reduced filling velocity during start-up of the filling.Type: GrantFiled: June 13, 2002Date of Patent: March 16, 2004Assignee: Disa Industries A/SInventor: Jan Bechmann Johansen
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Patent number: 6704693Abstract: The present invention provides a method and apparatus for analyzing the structural response of an object having an outer surface comprising a plurality of surface portions, the method including: forming a three dimensional model of said object, said model comprising a surface mesh representative of said outer surface and comprising a plurality of eccentric shell elements, wherein each of said elements is defined by a plurality of nodes on said surface and each of said nodes has one or more degrees of freedom; assigning to each of said elements a thickness indicative of half of the thickness of said object at said respective element; defining, for each of said elements, a reference surface that includes the nodes of said respective element and that is coincident with said surface mesh at said respective element; for a pair of opposed portions of said surface, establishing a constraining relationship between said degrees of freedom of each of said nodes on the first of said opposed portions and said degrees ofType: GrantFiled: October 16, 2000Date of Patent: March 9, 2004Assignee: Moldflow PTY LTDInventors: Zhi Liang Fan, Rong Zheng, Hua Gang Yu, Peter Kenneth Kennedy
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Patent number: 6703025Abstract: Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful selection of the proteins, fragments, or antibodies, a vaccine is provided that imparts protection against a broad spectrum of Staphylococcus bacterial strains and against proteins that are expressed at different stages of the logarithmic growth curve. In one embodiment of the invention, a composition is provided that includes at least a collagen binding protein or peptide (or an appropriate site directed mutated sequence thereof) such as CNA, or a protein or fragment with sufficiently high homology thereto, in combination with a fibrinogen binding protein, preferably Clumping factor A (“ClfA”) or Clumping factor B (“ClfB”), or a useful fragment thereof or a protein or fragment with sufficiently high homology thereto.Type: GrantFiled: August 31, 1999Date of Patent: March 9, 2004Assignees: Inhibitex, Inc., The Provost Fellows and Scholars of the College of The Holy and Undivided Trinity of Queen Elizabeth near Dublin, The Texas A&M University SystemInventors: Joseph M. Patti, Timothy J. Foster, Magnus Hook
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Patent number: 6699812Abstract: Epoxidation catalyst based on titanium zeolite in the form of extruded granules. Use of this catalyst in the synthesis of epoxides, preferably 1,2-epoxy-3-chloropropane or 1,2-epoxypropane, by reacting an olefinic compound, preferably allyl chloride or propylene, with a peroxide compound, preferably hydrogen peroxide. Process for the preparation of an epoxide, preferably 1,2-epoxy-3-chloropropane or 1,2-epoxypropane, by reacting an olefinic compound, preferably allyl chloride or propylene, with a peroxide compound, preferably hydrogen peroxide, in the presence of the aforementioned catalyst.Type: GrantFiled: January 25, 2002Date of Patent: March 2, 2004Assignee: Solvay SAInventors: Michel Strebelle, Jean-Pierre Catinat
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Patent number: 6698936Abstract: A tool for pre-stressing of two races to be welded to one another includes a hub having a cylindrical lateral hub wall and a tubular chuck having a cylindrical lateral chuck wall coaxially received and movable in the lateral hub wall. One of the lateral walls has a cylindrical face of revolution for radially supporting and centering the two races. A first axial abutment is immovable with respect to the chuck and against which a first free axial face is engageable, while a second axial abutment is immovable with respect to the hub and against which a second free axial face is engageable. A coaxial mechanism for axially moving the chuck towards the hub and hence for tightening the second axial abutment axially towards the first axial abutment is provided such that the two races therebetween are tightened against one another until a pre-determined pre-stress value is obtained.Type: GrantFiled: January 8, 2003Date of Patent: March 2, 2004Assignee: Sagem SAInventors: Hervé Dardelet, Michel Augot, Marc Jenger
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Patent number: 6698494Abstract: The present invention relates to a method for casting ferrous or heavy metal articles in vertically parted sand moulds of a mould string plant through an inlet below or aside the mould cavity, by filling the moulds with molten metal by counter-gravity delivery using a source of pressure. The pressure is varied during the filling procedure to steer the flow speed and impact on the mould of the molten metal upon complete filling of the mould cavity is reduced.Type: GrantFiled: July 23, 2001Date of Patent: March 2, 2004Assignee: Disa Industries A/SInventors: Preben Nordgaard Hansen, Uffe Andersen, Laurits Aage Berg Larsen
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Patent number: 6692423Abstract: A method for making a cigarette container wherein a hollow container body is constructed having an open end which includes a step portion defining a surrounding rim and interior abutments. A plug is prepared which is sized to be received between the rim of the body and to abut the abutments. The plug includes a main plate, a metal layer attached to the main plate, and a heat activated adhesive located adjacent the metal layer and positioned to be immediately adjacent the step portion. An induction heating device is then located adjacent the open end of the body, and activated to heat the metal layer and hence to heat the adjacent adhesive so that after cooling the plug is bonded to the body by the adhesive and the plug thus permanently closes the open end of the body.Type: GrantFiled: November 29, 2001Date of Patent: February 17, 2004Assignee: SASIB Corporation of AmericaInventors: Walter Bohdan, Samuel D. Johnson, Robert H. Coultrip, William M. Phillips, Carl E. Copeland, William E. Hazlett
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Patent number: 6692720Abstract: Process for the production of sodium chloride crystals from a sodium chloride brine contaminated by potassium chloride and sulphate ions, according to which a calcium compound (32) is added to the brine (48) to crystallize glauberite (35), which is isolated, the resulting aqueous solution (36) is subjected to evaporation to crystallize sodium chloride (40), which is collected, and the aqueous mother liquor (41) from the crystallization of the sodium chloride is subjected to cooling (42) to crystallize glaserite (45).Type: GrantFiled: August 27, 2001Date of Patent: February 17, 2004Assignee: Solvay (Societe Anonyme)Inventors: Leon Ninane, Cédric Humblot, Pascal Gerard
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Patent number: 6692739Abstract: A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection or preparation of a donor plasma pool with high antibody titers to carefully selected Staphylococcus adhesins or MSCRAMMs, or fragments or components thereof, or sequences with substantial homology thereto. The donor plasma pool can be prepared by combining individual blood or blood component samples which have higher than normal titers of antibodies to one or more of the selected adhesins or other proteins that bind to extracellular matrix proteins, or by administering carefully selected proteins or peptides to a host to induce the expression of desired antibodies, and subsequently recovering the enhanced high titer serum or plasma pool from the treated host.Type: GrantFiled: August 31, 1999Date of Patent: February 17, 2004Assignees: Inhibitex, Inc., The Provost Fellows and Scholars of The College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin, The Texas A&M University SystemInventors: Joseph M. Patti, Timothy J. Foster, Magnus Hook
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Patent number: 6692110Abstract: A developing system for a bore matrix in a printer using toner in the form of a dry toner powder, and comprising a feeder brush (3) which receives toner from a toner container (1), a printer brush (5) receiving toner from the toner feeder brush (3) and transporting same through bores of a bore matrix (8) and down to a document (9) to be printed, and means (15) for charging the toner particles by mechanically rubbing the toner particles (2) against the printer brush (5), and in which a means (19) may be provided for ripping free the charged toner particles (2), so that said particles form a cloud (7) of charged toner particles (2) adjacent the bore matrix (8), which pass down to the document (9) to be printed through open bores of the bore matrix (8).Type: GrantFiled: November 5, 2002Date of Patent: February 17, 2004Assignee: Jarfalla Digital Filter Printer ABInventor: Per Sundström