Abstract: The present application describes modulators of MIP-1? or CCR-1 of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein n, ring A, T, V, X, R1, R2 and R8, are defined herein. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.
Abstract: Stable, cold water soluble, ready for use starch aldehyde compositions and the method of preparation of such compositions wherein an aqueous dispersion of a converted starch acetal is hydrolyzed under acidic conditions to form the starch aldehyde which is then spray dried into a cold water soluble starch aldehyde powder.
Type:
Grant
Filed:
November 5, 1998
Date of Patent:
July 24, 2001
Assignee:
National Starch & Chemical Investment Holding
Corporation
Inventors:
A. Levent Cimecioglu, Bjork Ohlhorst, Daniel B. Solarek, Douglas J. Slate, James L. Eden