Abstract: A temperature monitoring system employs a temperature detection means incorporated into an invasive device intended to be placed within a body during a magnetic resonance procedure. The temperature monitoring system is used to monitor temperature rises in tissue arising from the creation of electric fields within the tissue. These electric fields are created by the application of RF pulses during the course of a magnetic resonance procedure which induce electrical current in the invasive device. It the detected temperature rise exceeds a selected threshold, the temperature monitoring system can cause the magnetic resonance imaging system to either reduce RF power or terminate the procedure. An optical coupling may be used between the imaging or tracking RF coil and the MR receiver to eliminate heating induced by the application of RF pulses during the procedure.

Abstract: A novel RF coil attached to an invasive device, such as a catheter, is used to detect magnetic resonance (MR) signals for monitoring the position of the device within a subject and for the acquisition of high-resolution magnetic resonance images of the tissue surrounding the device. The novel coil is sensitive to a small volume of MR active tissue during tracking procedures, but is sensitive to a larger volume during imaging procedures. During tracking, the MR signals are detected in the presence of magnetic field gradients and thus have frequencies which are substantially proportional to the location of the coil along the direction of the applied gradient. Signals are detected responsive to applied magnetic gradients to determine the position of the coil in several dimensions. The position of the novel coil, and hence the device, as determined by the tracking system is superimposed upon independently acquired medical diagnostic images.

Abstract: A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet, and a large low-field magnetic resonance (MR) imaging magnet for the purpose of generating MR images of blood perfusion in tissue. A subject is positioned in a large low-field MR imaging magnet. A catheter is inserted into the patient at or near the root of a vessel supplying blood to a portion of tissue to be imaged. A fluid, intended to be used as a contrast agent is first passed through the small high-field polarizing magnet, causing a high degree of net longitudinal magnetization to be produced in the fluid. The fluid is then introduced into the subject through the catheter. Radiofrequency (RF) pulses and magnetic field is gradients are then applied to the patient as in conventional MR imaging. Since the fluid has a larger longitudinal magnetization, before the MR imaging sequence, the fluid produces a much larger MR response signal than other tissue.

Abstract: A system of accurately positioning a manufactured part in a calibrated position, involves positioning the part on a structure. Adjusting the part on the structure such that points on the surface of the part known to be accurate and drilling notches in the part at known locations. Distances from the surface of the part to the structure in `x` and `z` directions, and a rotation angle .theta. are measured. The part is then placed in a fixture having a nest plate with pins which hold the part by the notches thereby defining an axis through the part. A `z` stop is adjusted to the measured `z` distance which stops rotation of the part about the axis between the pins. An `x` stop is set to the measured x distance which stops translation of the part along the axis between the pins. The nest plate is pivotally attached to the base plate allowing the nest plate to rotate with respect to the base plate the rotational angle .theta.. This results in calibrated positioning of the part allowing maximum access to the part.

Abstract: An enhanced reality maintenance system operates one or more remotely operated vehicles (ROVs) in a hazardous or inaccessible environment. A computer model of the environment is created from spatial parameters provided to the system. Positions and orientations of moving objects are monitored. The projected course of the moving objects is extrapolated and constantly updated. An automated flight planner, receives desired destinations from an operator, analyzes the environment, the projected courses of moving objects and planned trajectories of other ROVs, and selects a planned trajectory of a selected ROV through the environment without collision.

Abstract: Instruments are constructed of a carbon fiber material optionally doped with a doping agent such as iron oxide, the instrument having a magnetic susceptibility being adjusted to a portion of a subject being imaged. Therefore there is little effect upon the lines of magnetic flux and the magnetic field homogeneity, reducing distortion in an MR image. These carbon fiber instruments exhibit virtually no magnetic torsional forces when inserted into a magnetic field. This is important, for example when the instrument is a scalpel. Doped carbon fiber has minimal affect on radiofrequency fields. The instruments do not affect the homogeneity of an applied homogeneous magnetic field or an applied radiofrequency field. Doped carbon fiber exhibits a rigidity large enough to allow construction of high strength instruments such as biopsy needles. It also has the ability to retain a sharp edge, allowing construction of scalpels and cutting instruments.

Abstract: An interactive three-dimensional (3D) pointing device for selecting points within a subject employs a tracking device which determines the position of the operator, a semi-transparent screen positioned by the operator and the subject and provides this information to a model workstation. The model workstation superimposes computer graphic images of internal structures of the subject on a the semi-transparent screen through which the operator is viewing the subject. The superimposed image is derived from image data either previously generated and stored or obtained with an imaging system. The images of the internal structures are registered with the operator's view of the external structures of the operator. The operator interactively views internal and external structures and the relation between them simultaneously, while moving the screen to select 3D target points at an image depth within the subject. Optionally other input devices may be used to identify current `target points` as selected points.

Abstract: A group visualization system allowing users of a group, either at a local site or a remote site to view images personalized to each users specific needs. Each user of the team interactively selects personalize viewing parameters, such as portions of the model to be displayed and the angle to view the model. Each user may select an overlay map to be superimposed on the model and displayed in the same manner which the model is displayed. A user who is an electrical engineer may select a voltage overlay, which a mechanical engineer may select a stress/strain overlay of the same model. Each user may select the parameters specified by another user or users, either at the local site or a remote sites, to see what they are viewing. Each user has access to a pointer which allows each user to specify a location which a symbol is superimposed and is visible to selected users. This results in a tool allowing users of a group at various sites to act as a team interact with each other.

Abstract: An adjustable subject positioning device employs a `pegboard `in which supports may be placed in a variety of locations. The supports hold various portions of the subject in order to position the subject such that the subject is in the position which accentuates an abnormality. An example would be to seat the subject and adjust the support such that the subject is in a sitting position with his upper torso bending over with his head towards his knees. This would accentuate bulges in disks between vertebrae. Once in this position, medical imaging may be accomplished making the abnormality much more visible than if the subject were in a prone position. Additionally, sensors connected to a position calculation device may store a representation of the where the supports were located during the image acquisition, and an indication of the locations of these supports be played back during viewing of the image.

Abstract: A tracking system monitors the position of a device within a subject and superimposes a graphic symbol on a diagnostic image of the subject. Registration of the tracked location with the diagnostic image is maintained in the presence of subject motion by monitoring subject motion and adjusting the display to compensate for subject motion. Motion monitoring can be performed with ultrasonic, optical or mechanical methods. The display can be adjusted by modifying the displayed location of the device or it can be adjusted by translating, rotating or distorting the diagnostic image.

Abstract: Radiofrequency (RF) and magnetic field gradient pulse sequences employ Time-of-Flight (TOF) strategy to selectively create transverse spin magnetization which is then maintained for a selected period of time and then imaged in order to generate a vessel selective magnetic resonance angiogram. The pulse sequence employs a spatially selective excitation pulse which is used to create transverse spin magnetization in a selected region of a subject. This region typically is made to include the root of the vessel to be imaged. After excitation, transverse magnetization is maintained with a series of refocusing RF pulses while the blood moves along the vessel. The transverse magnetization is then sampled at one or more selected times after excitation with conventional imaging strategies.

Abstract: The present invention determines the epicardial boundary, being a closed curve dividing the myocardium from the tissue and blood surrounding the left ventricle. A mean and standard deviation is determined for pixels of a medical image of the subject's myocardial tissue. These are used to define a "goodness function" over the image which is positive for pixels statistically likely to be myocardial tissue, and negative for other pixels. An initial curve for modeling the epicardium in radial coordinates starts with a curve of inner myocardial boundary obtained my conventional imaging techniques. This curve is then iteratively updated to maximize the total "goodness function" of the region encompassed.

Abstract: A multi-dimensional data set acquired by non-intrusive means with the use of a surface coil of internal structures of internal structures of a subject. The data set is adjusted for the differential sensitivity of the surface coil with respect to distance from the coil and angle in relation to the coil. The adjusted data set then is searched for abrupt changes in value in the data set indicating surfaces. The surfaces then may be manipulated, shaded, color coded and displayed. This is particularly useful in when employed on a data set which images blood for providing surface images of coronary arteries of the subject for non-invasive detection of occlusion and stenosis.

Abstract: A distance measurement system employs a monochromatic coherent light source which produces an outgoing ray which impinges upon a target reflector which reflects the beam back as a reflected beam to an interferometry detector. A portion of the outgoing ray also is delivered to the interferometry detector. As the target reflector position is changed, the interferometry detector continuously calculates changes in distance of the target reflector. The orientation angles of the target reflector are constantly and automatically adjusted so that the reflected light beam accurately strikes the interferometry detector. A misalignment detector senses the elevation offset and the azimuth offset of the target reflector and creates corresponding signals.

Abstract: A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet, and a large, possibly low-field magnetic resonance (MR) imaging magnet for the purpose of generating MR angiograms of selected blood vessels. A subject is positioned in a large MR imaging magnet. A catheter is inserted into the patient at or near the root of a vessel tree to be imaged. A fluid, intended to be used as a contrast agent is first cooled and frozen, and then passed through the small high-field polarizing magnet where it becomes highly polarized. The frozen fluid is then heated and melted to physiologic temperatures and introduced into the subject through the catheter. Radiofrequency (RF) pulses and magnetic field gradients are then applied to the patient as in conventional MR imaging.

Abstract: A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet, and a large magnetic resonance (MR) imaging magnet for the purpose of generating MR images of selected body cavities. A subject is positioned in a large low-field MR imaging magnet. A substance, intended to be used as a contrast agent is first cooled, and then passed through the small high-field polarizing magnet where it becomes highly polarized. The substance is then heated to physiologic temperatures, vaporized, and introduced into the subject through a transfer conduit as a vapor. Radiofrequency (RF) pulses and magnetic field gradients are then applied to the patient as in conventional MR imaging. Since the vapor is highly polarized, it can be imaged even though it has a much lower density than the surrounding tissue.

Abstract: A method is described which corrects magnetic field inhomogeneities in a magnetic resonance (MR) imaging system that takes into account the effects of a subject on the magnetic fields. A magnetic resonance sequence is applied to the subject to extract MR response signals from the subject indicating the magnetic field inhomogeneity over space. The changes of magnetic field inhomogeneity with a change in radial variable .rho. (or r, in a cylindrical coordinate system) are calculated. A derivative with respect to a radial variable is calculated of a generalized 3D infinite series polynomial, such as a Legendre polynomial expressed in spherical coordinates. These inhomogeneity changes are then fit to 3D polynomial derivative to result in coefficients [dI.sub.c ]. Similarly coefficients of a derivative shim coil calibration matrix [dM] are determined for each shim coil modeling the effect of each shim coil is on the magnetic field within the imaging volume.

Abstract: A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet, and a large low-field magnetic resonance (MR) imaging magnet for the purpose of generating MR angiograms of selected blood vessels. A subject is positioned in a large low-field MR imaging magnet. A catheter is inserted into the patient at or near the root of a vessel tree desired to be imaged. A hydrogen gas is first cooled and condensed into a liquid state, and then passed through the small high-field polarizing magnet where it becomes highly polarized. A contrast fluid is then made by chemically combining the polarized hydrogen with oxygen to obtain highly polarized water. The water is then heated to physiologic temperatures and, if desired, made more physiologically compatible with the addition of substances such as salts. The physiologically conditioned polarized fluid is then introduced into the subject through the catheter.

Abstract: A magnetic resonance (MR) active invasive device system employs a small, high-field polarizing magnet having a toroidal geometry, and a large low-field magnetic resonance (MR) imaging magnet for the purpose of generating MR angiograms of selected blood vessels. A subject is positioned in a large low-field MR imaging magnet. A catheter is inserted into the patient at or near the root of a vessel tree to be imaged. A fluid, intended to be used as a contrast agent is first passed through the small high-field polarizing magnet, causing a great deal of net longitudinal magnetization to be produced in the fluid. The fluid is then introduced into the subject through the catheter. Radiofrequency (RF) pulses and magnetic field gradients are then applied to the patient as in conventional MR imaging.

Abstract: A virtual internal cavity inspection system non-invasively provides images of cavities of a subject from a viewpoint within the cavity. An acquisition unit acquires imaging information about internal structures of a subject. This imaging information is segmented into separate structures, and a 3D surface model is constructed. An operator views an image of the 3D model to select a goal viewpoint and a start viewpoint. A viewpoint path is created linking the start viewpoint and the goal viewpoint. Images are created with a viewpoints along the viewpoint path. A variety of additional visualization techniques aid the viewer's localization of the current image viewpoint, and its relation to the subject.