Patents Represented by Attorney Leoniede M. Vidas, Arrett & Steinkraus Brennan

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  • Azavesamicols
    Patent number: 5876694
    Abstract: A method for non-invasively mapping cholinergic innervation in a living brain comprises injecting the brain with a radiolabelled vesamicol (hydroxylated phencyclidine (PCP) isomer trans-2-(4-phenyl-piperidino)cyclohexanol) derivatives with anticholinergic properties termed herein "azavesamicols" in which the cyclohexyl group of vesamicol is replaced with heterocycle of similar size, the piperidyl ring. The radiolabel is then detected externally with a photoscanning device.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: March 2, 1999
    Assignees: Regents of the University of Minnesota, Regents of the University of California
    Inventors: Simon Mbua Ngale Efange, Stanley M. Parsons