Abstract: A device and method are provided for managing the treatment of a patient with respiratory disorders or symptoms. Respiratory parameters are sensed and recorded and communicated to an external device to provide information to a patient and/or provider for further treatment or diagnosis. Also respiratory disorders such as apnea or hypoventilation may be treated by electrically stimulating the diaphragm muscle or phrenic nerve in response to a sensed respiratory parameter or characteristic.

Abstract: An automated tissue retention system generally comprises an oral appliance retractably coupled to a covering which is secured to an anterior portion of the tongue. Once placed within a subject's mouth, the appliance may be maintained in a closed configuration while the subject's mouth remains closed. However, as the subject sleeps and the tongue becomes hypotonic, the subject's mouth typically opens during a sleep disordered event. The appliance may be actuated by the separation between the mandible and maxilla to have greater tension and thus retract or pull anteriorly the covering adhered to the tongue. As the covering pulls the tongue anteriorly or maintains a position of the tongue, the base of the tongue may be inhibited or prevented from collapsing posteriorly against the phryngeal tissue walls and thereby allow the subject to breathe normally.

Abstract: Energy harvesting systems are described in which electroactive materials, such as dielectric elastomers, may be utilized to absorb the shocks, bumps, and vibrations from the road or path to generate energy which is captured and stored for use in the vehicle to provide additional power for any number of uses. Other devices and systems, such as household appliances which dissipate vibrational energy, may also incorporate any number of the dielectric elastomer generators.

Abstract: The present invention relates to a gaming and/or entertainment device having a plurality of wager fields which can be covered individually or group-wise by a wager of a player, as well as having a plurality of winning fields of which one or more can be selected by means of a winnings determination means. Bet display means are provided at the winning fields for marking the winning fields which produce a win according to the bets made, with a detection apparatus being associated with the wager fields for the detection of the wager fields respectively covered by a bet and with a control apparatus being provided for the control of the bet display means at the winning fields in dependence on the wager fields covered by bets and detected by the detection apparatus.

Abstract: A device and method is provided for therapeutic stimulating, augmenting, manipulating and/or controlling breathing, in combination with stimulation of auxiliary respiratory nerves or muscles including the upper airway tract, chest wall muscles or abdominal muscles. Stimulation may be provided, for example, to augment breathing or to prevent closing of the upper airway during therapeutic stimulation. Stimulation may be also provided to the Hypoglossal nerve during exhalation.

Abstract: Methods and apparatus for transmitting vibrations via an electronic and/or actuator assembly through a custom-fitted dental appliance are disclosed herein. The customized fitting is done by the user. The assembly may be attached, adhered, or otherwise embedded intra-orally on a tooth or oral tissue. The electronic and actuator assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating actuator element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.

Abstract: Apparatus and methods are provided for thermally and/or mechanically treating tissue, such as valvular structures, to reconfigure or shrink the tissue in a controlled manner. Mechanical clips are implanted over the leaflets of a valve, e.g., in the heart, either alone or after thermal treatment to cause the valve to close more tightly. The clips are delivered by a catheter and may be configured to traverse directly over the valve itself or to lie partially over the periphery of the valve to prevent obstruction of the valve channel. The clips can be coated with drugs or a radiopaque coating. Alternatively, individual anchors with a tensioning element, like a suture, may be used to approximate the valves towards each other. The catheter can also incorporate sensors or energy delivery devices, e.g., transducers, on its distal end.

Abstract: Electrode placement and connection systems are described which allow for the electrical connection and maintenance of one or more electrodes positioned on a substrate which is subjected to a variety of mechanical stresses. Such a system may include an imaging hood having an aperture through which transparent fluid is flowed and one or more electrodes positioned along or about the hood. As the hood is configured between a low-profile and opened configuration, these electrodes may remain electrically coupled despite the mechanical stresses subjected to the electrodes and the connections thereto.

Abstract: The invention relates to an actuator for a dispenser device for spraying contents of a receptacle that is pressurized or of a receptacle that has a pump, the actuator comprising a channel connectable to a receptacle outlet on one side of the actuator for receiving the pressurized contents of the receptacle, said channel having an orifice for spraying the contents on another side of the actuator, wherein an inlet connects the channel with a volume chamber, wherein the orifice has a valve for opening and closing the orifice, the valve biased by biasing means in the closed position, wherein the inlet has inlet reduction means for reducing the size of the inlet to the volume chamber. The invention is characterized in that the inlet reduction means comprises a flexible element.

Abstract: A lunch box assembly having a main housing having a lid rotatably, hingedly attached to a base to provide access to an opened interior of one or more compartments is disclosed. The lid can have ferrously magnetic material and recesses to accept magnets. The magnets can be shaped to fit the recesses. The base can have compartments aligned with corresponding compartments in the lid. The base and the lid can form one or more closed food storage compartments that separate the contents from the neighboring compartments. A latch on the base and lid can produce a clamping force on a small lidded container or containers placed in one or more of the compartments. The clamping force can clamp the lidded container closed and prevent leakage of fluids in the container.

Abstract: A system level scheme for networking of implantable devices, electronic patch devices/sensors coupled to the body, and wearable sensors/devices with cellular telephone/mobile devices, peripheral devices and remote servers is described.

Abstract: Shape memory dental retention systems which facilitate the adjustment or removal of an oral appliance, e.g., a crown or bridge, from a reconfigurable abutment assembly are described. The adjustable abutment assembly may be secured to an anchoring implant bored into the bones within the mouth. The abutment assembly has a projecting abutment portion with one or more shape memory material sleeves or plates or elements extending along the abutment. Each of the sleeves has a length with at least one curved or arcuate portion. Energy may be applied to the elements such that the arcuate portion flattens to allow for the oral appliance to be placed thereupon while removal of the energy allows the elements to reconfigure into its curved configuration thereby locking the oral appliance to the abutment. Removal of the oral appliance may be effected by reapplication of energy to the elements.

Abstract: This invention relates to surgical instruments for applying energy to tissue. In one embodiment, an elongated introducer has a handle portion that includes an interior chamber that is supplied with a biocompatible liquid under pressure. An energy source causes a liquid-to-vapor phase change within the interior chamber and ejects a flow of vapor media from the working end of the introducer. The flow of vapor is controlled by a computer controller to cause a selected pressure, a selected volume of vapor, and an optional aspiration of vapor condensate. Contemporaneous with tissue contact, the vapor undergoes a vapor-to-liquid phase transition which delivers large amount of energy to the targeted tissue. In one embodiment, the system is configured for volumetric removal of tissue by means of high velocity ejection of a vapor media from a first vapor port proximate to soft tissue wherein the vapor-to-liquid phase change of the media applies energy to the tissue.

Abstract: Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.

Abstract: Sterilization methods for implantable prostheses are described where a polymeric stent may be sterilized, e.g., via ETO sterilization, at a temperature below a glass transition temperature of the stent. A separate delivery catheter may be sterilized separately and the stent and delivery catheter may then be combined in an aseptic or semi-aseptic environment and sterilized as an assembled system such that the requirements for sterilizing the system are relatively lower. Additionally and/or alternatively, valve and filter assemblies may be used with an optional mandrel assembly for maintaining sterility of the internal components of a catheter system.

Abstract: Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy.

Abstract: Systems and methods are disclosed for capturing sound for communication by mounting one or more intra-oral microphones to capture sound; and mounting a mouth wearable communicator in the oral cavity to communicate sound with a remote unit.

Abstract: Systems for manufacturing oral-based hearing aid appliances utilizing various manufacturing methods and apparatus are described herein. The oral appliance may have an electronic and/or transducer assembly for receiving incoming sounds and transmitting processed sounds via a vibrating transducer element coupled to a tooth or teeth. The oral appliance may be formed or fabricated via three-dimensional digital scanning systems or via impression molding to create a housing for the electronics and/or transducer assembly as well as to securely conform the appliance to the user's dentition.

Abstract: Various medical devices and methods for cutting and/or evacuating tissue are provided. The devices and methods may utilize a reciprocating mechanism or motor powered by suction from a vacuum source. The medical devices and methods may be used on tissue in various regions of a patient's body and for treating various conditions, e.g., for performing a polypectomy or discectomy.

Abstract: A method of distributing particles in a flow of gas and a needleless syringe for use in the needleless injection of particles into the skin or mucosa of a vertebrate subject are disclosed. The syringe includes a convergence which reduces pressure of the gas flowing in the gas flow path due to the Venturi effect such that particles initially located outside of the gas flow path are drawn into the gas flow path under the action of the reduced pressure and become entrained in the gas. An exit nozzle accelerates the particles so entrained. In another aspect of the invention, there is provided a method of creating a gas flow in a needleless syringe which comprises flowing gas through a first convergence into a chamber to form a transsonic gas jet in the chamber and passing the gas jet from the chamber into a second convergence and along the nozzle.