Patents Represented by Attorney, Agent or Law Firm Leydig, Voit & Meyer
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Patent number: 8071294Abstract: The present invention relates to compositions and methods for sensitizing cancer therapy. The invention provides such compositions comprising a SPARC family polypeptide or polynucleotide, as well as recombinant cells containing a SPARC family polypeptide or polynucleotide. The compositions and methods of the invention are useful in in vitro study of cancer therapy resistance, as well as ex vivo and in vivo therapy of cancer.Type: GrantFiled: November 25, 2009Date of Patent: December 6, 2011Assignee: Dana-Farber Cancer InstituteInventors: Isabella T. Tai, Lan Bo Chen
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Patent number: 7918296Abstract: A cooling system (500) for an electric drive system includes a cooling duct (502) extending between a first component and a second component. A motor (336) driven fan (510) creates an airflow within the duct. A first temperature sensor measures a first temperature of the first component and a second temperature sensor measures a second temperature of the second component. An electronic controller (540) receives the first temperature and calculates a first temperature difference between the first temperature and the first temperature limit (802) to generate a first command (836) for the motor (336). A second temperature difference between the second temperature and the second temperature limit (802) generates a second command (836) for the motor (336). The controller (540) then selects the greater of the first command (836) and the second command (836) to yield the maximum command (836), and controls the motor (336) based on the maximum command (836).Type: GrantFiled: September 15, 2008Date of Patent: April 5, 2011Assignee: Caterpillar Inc.Inventor: Suresh B. Reddy
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Patent number: 7792922Abstract: A method and system for monitoring the health of a networked client computer node include health service agent software that scans the client computer node upon which the agent is installed. The health service agent software transmits data to a health service data manager identifying the type of client node upon which the agent is installed to permit retrieval by the manager of a health service task list specifying rules and executables applied by the health service agent to an associated client node.Type: GrantFiled: March 5, 2008Date of Patent: September 7, 2010Assignee: Caterpillar Inc.Inventors: Greg R. Purcell, Steven G. Yarnot, Anthony Hobson
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Patent number: 7766419Abstract: A sliding panel arrangement for a vehicle wherein a panel is adapted to be coupled to a vehicle body, at least two linear bearings or at least one longitudinal member being disposed on the panel, the other of the at least two linear bearings or at least one longitudinal member being adapted to be coupled to the vehicle body. The longitudinal member is sized and disposed to slide within the linear bearings, the panel sliding between closed and open positions over a vehicle compartment.Type: GrantFiled: December 3, 2007Date of Patent: August 3, 2010Assignee: Caterpillar Paving Products inc.Inventors: Andrew James Krolnik, John Marsolek
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Patent number: 7738979Abstract: A control system for controlling one or more actuators in a machine in response to installation of a tool to the machine detects the installation of a tool to the machine and prompts a user of the machine to configure the operation of the controller with respect to at least one of the one or more actuators.Type: GrantFiled: November 1, 2007Date of Patent: June 15, 2010Assignee: Caterpillar Inc.Inventors: Benjamin B. Schmuck, Steven C. Budde
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Patent number: 7503445Abstract: A bill storage unit has a bill storage portion for storing bills and a bill validator which takes in a bill to validate the bill. A feeding device feeds the bill delivered from the bill validator to the bill storage portion along a feeding path. A correcting device removes a fold in the bill by applying a force stretching the bill, while the bill is being supported and guided along at least part of the feeding path.Type: GrantFiled: November 9, 2005Date of Patent: March 17, 2009Assignees: Aruze Corp., Seta Corp.Inventor: Kazuei Yoshioka
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Patent number: 7420998Abstract: A semiconductor laser device has a front surface electrode formed by Au plating, a rear surface electrode formed by Au plating, an anti-adhesive film only on the front surface electrode and made of a material that does not react with Au, and a coating film that covers an end face on a light emitting side and an end face opposite the light emitting side. The anti-adhesive films are located on the four corners of the front surface electrode.Type: GrantFiled: March 23, 2005Date of Patent: September 2, 2008Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Junichi Horie
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Patent number: 7190589Abstract: The electronic control enclosure includes devices and methods for removing heat energy from the electronic components of an electronic control unit. The components are mounted to a substrate and are protectively housed in an interior chamber of an environmentally sealed enclosure housing. Electrical communication is established with the components via a header assembly that includes plug receptacles. To remove heat generated by the components from the enclosure housing, one or more heat sinks are disposed through the enclosure housing such that the heat sinks have an interior surface exposed to the interior chamber and an exterior surface exposed to the exterior of the enclosure housing. In other embodiments, the enclosure housing may be made of a heat conductive material and the heat sink is integral with the enclosure housing. In one aspect, a spring urges the components against the interior surface. In another aspect, the components are mounted to and directly contact the interior surface.Type: GrantFiled: October 19, 2004Date of Patent: March 13, 2007Assignee: Cinch Connectors, Inc.Inventors: Arturo Caines, Bratislav Kostic, Thaddeus Rachwalski
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Patent number: 6909135Abstract: In the semiconductor storage device, a dummy P+ diffusion region which does not contribute to a storage operation is formed in the vicinity of two P+ diffusion regions constituting a storage node. Moreover, a dummy N+ diffusion region which does not contribute to the storage operation is formed in the vicinity of N+ diffusion regions FL210 and FL220 constituting a storage node. Consequently, a part of electrons generated in a P well region PW by irradiation of ? rays or neutron rays can be collected into the dummy N+ diffusion region FL250, and a part of holes generated in an N well region NW by the irradiation of the ? rays or the neutron rays can be collected into the dummy P+ diffusion region FL150.Type: GrantFiled: March 13, 2002Date of Patent: June 21, 2005Assignee: Renesas Technology Corp.Inventors: Koji Nii, Shoji Okuda
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Patent number: 6907173Abstract: Cores are embedded in a cladding, each core constituting a continuous optical path in which a first core end surface is exposed at a first end surface, and a second core end surface is exposed at a second end surface. Each of the continuous optical paths extends from the first core end surface to a mirror surface, is changed in direction at the minor surface, and then extends to the second core end surface. The first core end surfaces and the second core end surfaces are respectively arranged two-dimensionally at the first end surface and the second end surface.Type: GrantFiled: March 25, 2003Date of Patent: June 14, 2005Assignee: Mitsubishi Denki Kabushiki KaishaInventor: Seiki Hiramatsu
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Patent number: 6824074Abstract: An external mix air atomizing spray nozzle assembly having a nozzle body formed with liquid and air passages, a spray tip at a downstream end of the nozzle body having a nose portion that defines a liquid discharge orifice, and an air cap mounted in surrounding relation to the spray tip nose portion. The air cap defines an annular pressurized air orifice about the spray tip nose portion and a plurality of angled air passages disposed radially outwardly thereof. Pursuant to the invention, the spray tip nose portion has a frustoconical end tapering inwardly in a downstream direction which enhances air entrainment and minimizes liquid turbulence in a zone immediately in front of the air cap and around the spray tip nose portion to prevent undesirable build up of spray material on the exposed end surfaces of the spray tip nose portion and air cap.Type: GrantFiled: February 18, 2003Date of Patent: November 30, 2004Assignee: Spraying Systems Co.Inventor: Waclaw Komornicki
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Patent number: 6810863Abstract: A gas/air mixer assembly provides a Venturi metering system that may draw fuel from a zero governor, mix it with air to form a homogenous gas/air mixture for delivery to an internal combustion engine. The gas/air mixer assembly may also accept fuel under pressure from a gas metering valve or fuel injector for delivery to an internal combustion engine. The mixer includes an air horn, the relative position of which in relation to a shaped restriction body governs the air flow into the engine intake manifold. The flange of the air horn is configured to redirect the flow of air without generating significant turbulence, and providing a maximum velocity perpendicular flow to the injection of fuel to be mixed therein. The relative position of the air horn to the shaped restriction body is determined based on the cubic capacity and speed of the engine with which it is used.Type: GrantFiled: October 31, 2003Date of Patent: November 2, 2004Assignee: Woodward Governor CompanyInventors: Bryan Memmott, Mark A. Fisher, Jerry D. Hielkema
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Patent number: 6773692Abstract: The present invention provides a cost-effective method of producing pure hydrogen gas from hydride-based solid materials. The hydride-based solid material is mechanically processed in the presence of a catalyst to obtain pure gaseous hydrogen. Unlike previous methods, hydrogen may be obtained from the solid material without heating, and without the addition of a solvent during processing. The described method of hydrogen production is useful for energy conversion and production technologies that consume pure gaseous hydrogen as a fuel.Type: GrantFiled: June 12, 2002Date of Patent: August 10, 2004Assignee: Iowa State University Research Foundation, Inc.Inventors: Vitalij K. Pecharsky, Viktor P. Balema
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Patent number: 6736978Abstract: Method and apparatus for manipulating and monitoring analyte flowing in fluid streams. A giant magnetoresistive sensor has an array of sensing elements that produce electrical output signals which vary in dependence on changes in the magnetic field proximate the sensing elements. The analyte is included in a stream, such that the stream has a magnetic property which is dependent on the concentration and distribution on the analyte therein. The stream is flowed past the giant magnetoresistive sensor and in sufficiently close proximity to cause the magnetic properties of the stream to produce electrical output signals. The electrical output signals are monitored as an indicator of analyte concentration or distribution in the stream flowing past the GMR sensor. Changes in the magnetic field produced by the background stream are introduced by analyte molecules, whose presence in the flow past the GMR will effect the output reading.Type: GrantFiled: December 13, 2001Date of Patent: May 18, 2004Assignee: Iowa State University Research Foundation, Inc.Inventors: Marc D. Porter, Jing Ni, G. Brent Dawson, Ruth Shinar, Robert J. Lipert, Michael C. Granger, Mark Tondra
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Patent number: 6657004Abstract: The present invention provides a film for packaging chemical agents, which contains an oxyalkylene unit-containing polyvinyl alcohol resin (A) and a carboxyl-containing polyvinyl alcohol resin (B), and preferably further containing a sulfo-containing polyvinyl alcohol resin (C). This film shows fine solubility in water even after a long-term packaging of an acidic chemical agent or alkaline chemical agent, and is superior in mechanical strength. Thus, the film for packaging chemical agents of the present invention is suitably used for packaging a chemical agent, such as powdered soap, synthetic detergent, agricultural chemical, antibacterial, deodorant, insecticide and the like, which is cast into water when in use.Type: GrantFiled: May 15, 2001Date of Patent: December 2, 2003Assignee: The Nippon Synthetic Chemical Industry Co., Ltd.Inventor: Tomoyoshi Mizutani
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Patent number: 6575587Abstract: A light that is mounted on a clamp. The clamp is configured to be attached to different locations on a user's body, and is sufficiently sturdy so that it can support the light in an illumination direction that is fixed relative to the user's body. The light is connected by a cord to a power supply, such as a battery pack or an AC adapter. If a battery pack is used, the battery pack may also include a mechanism, such as a clip, for attaching the battery pack to the clothing or belt of a user. A headband is provided to which the clamp may be attached. The light is pivotally attached to the clamp so the light may be pivoted to illuminate in a desired direction. In addition, the light is rotatably mounted on the clamp arm, permitting the light to illuminate in a wide variety of different angles.Type: GrantFiled: July 26, 2001Date of Patent: June 10, 2003Assignee: The Coleman Company, Inc.Inventors: Steven M. Cramer, Keith Skidmore, Kelly Merl Wright, Gary Israel
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Patent number: 6492596Abstract: A foamable composition containing a base polymer containing a polyethylene mixture of a low density-polyethylene having a density of 0.91-0.925 g/cm3 and a high density polyethylene having a density of 0.94-0.97 g/cm3, and a fluororesin powder and/or a boron nitride powder as a nucleator, wherein the high density polyethylene has an swelling ratio smaller than that of the low density polyethylene and a melt flow rate greater than that of the low density polyethylene, and is contained in a proportion of not less than 50 percent by weight of the polyethylene mixture, and the base polymer has a shear viscosity (temperature:170° C., shear rate:1216 sec−1) of not more than 3150 poise, and a coaxial insulating cable having an electrically insulating layer formed of a foam having an expansion ratio of not less than 70% and obtained by foaming the above foamable composition are provided.Type: GrantFiled: July 14, 2000Date of Patent: December 10, 2002Assignee: Mitsubishi Cable Industries, Ltd.Inventors: Takashi Higashikubo, Hirokazu Kuzushita, Akito Niboshi
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Patent number: 6429881Abstract: A method and system for viewing interface description documents, such as Web pages, performs a transition between a first graphic element and a second graphic element which are displayed according to the interface description document being viewed. To allow proper display of the graphic elements over a background, a transparency mask for each of the first and second graphic elements is generated and used in the image transition process. A display image, which is drawn on a video display for viewing, is initialized to contain the first graphic element. During the transition, selected pixels of the display image are replaced by corresponding pixels of the second graphic element over multiple frames until the display image has changed to contain the complete second graphic element.Type: GrantFiled: December 3, 1997Date of Patent: August 6, 2002Assignee: Microsoft CorporationInventor: Thomas W. Olsen, IV
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Patent number: D503612Type: GrantFiled: August 26, 2003Date of Patent: April 5, 2005Assignee: Pierce Biotechnology, Inc.Inventors: Kay Krebsbach, Jim Sendecke, Stan Reed, Kathleen Mitchell Abendroth
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Patent number: D443481Type: GrantFiled: April 26, 2000Date of Patent: June 12, 2001Assignee: Brabantia Nederland B.V.Inventor: Rudolphus Cornelis Henricus Daams