Patents Represented by Attorney, Agent or Law Firm Lisa M. DiRocco, Esq.
  • Crystal structure of cPLA2 and methods of identifying agonists and antagonists using same
    Patent number: 6801860
    Abstract: The present invention provides for crystalline cPLA2. The crystal structure of cPLA2 has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of cPLA2 activity and membrane binding using such models are also disclosed.
    Type: Grant
    Filed: February 15, 1999
    Date of Patent: October 5, 2004
    Assignee: Genetics Institute, LLC
    Inventors: Andrea Dessen, William S. Somers, Mark L. Stahl, Jasbir S. Seehra