Abstract: A new receptor for fibroblast growth factor has been cloned and expressed. The recombinant receptor is useful for inhibiting FGF activity, and for screening compounds for binding activity similar to that of FGF. A soluble, truncated recombinant receptor is also prepared, and is capable of binding FGF.
Type:
Grant
Filed:
July 20, 2000
Date of Patent:
January 18, 2005
Assignee:
Chiron Corporation
Inventors:
Michael C. Keifer, Pablo D. T. Valenzuela, Philip J. Barr