Patents Represented by Attorney, Agent or Law Firm Lois K Ruszala
  • Patent number: 5852199
    Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C.dbd.O, CH.sub.2 or SO.sub.2 ; Y is C.dbd.O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: December 22, 1998
    Assignee: Dade Behring Inc.
    Inventor: Chengrong Wang
  • Patent number: 5851779
    Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C=O, CH.sub.2 or SO.sub.2 ; Y is C=O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: December 22, 1998
    Assignee: Dade Behring Inc.
    Inventor: Chengrong Wang
  • Patent number: 5830768
    Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C.dbd.O, CH.sub.2 or SO.sub.2 ; Y is C.dbd.O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: November 3, 1998
    Assignee: Dade Behring Inc.
    Inventor: Chengrong Wang
  • Patent number: 5821342
    Abstract: The present invention provides a novel carbamazepine hydrazide compound suitable for covalent attachment to a polymer particle reagent, having the general formula ##STR1## The present invention also provides a novel carbamazepine acid compound suitable for attachment to proteins for the production of carbamazepine immunogens. The carbamazepine antigen of the present invention has the following general structure: ##STR2## where X is C=O, CH.sub.2 or SO.sub.2 ; Y is C=O, CH.sub.2, SO.sub.2 ; R is an alkyl and P is a protein or a hapten.
    Type: Grant
    Filed: April 3, 1997
    Date of Patent: October 13, 1998
    Assignee: Dade Behring Inc.
    Inventor: Chengrong Wang
  • Patent number: 5770390
    Abstract: Lipohaptens of the general formula I(X).sub.m --R--Y--(S).sub.n --P (I)whereinR is a hydrocarbyl backbone having from 2 to 30 carbon atomsX is a hydrocarbyl radical having from 6 to 30 carbon atoms, which is linked to R via a bonding group containing one or more heteroatomsm is an integer from 1 to 5P is a polypeptide or polysaccharide residue having from 2 to 100 aminoacid or glycosyl unitsY is a functional group capable of binding to a free amino group of the polypeptide P or a carboxy, hemiacetal or hydroxy group of the polysaccharide PS is a difunctional spacer group, the functional groups thereof being capable of binding with the functional groupY on the one hand and a free amino, carboxy or hydroxy group of the polypeptide or polysaccaride P on the other hand, andn is 0 or 1and their use in immunoreactions for determining antibodies and antigens, respectively.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: June 23, 1998
    Assignee: Dade International Inc.
    Inventor: Wilhelm Stoffel
  • Patent number: 5739036
    Abstract: An analyzer apparatus for analyzing components of a sample has a conduit and an electrochemical sensor in the conduit. The sample is passed through the conduit using a carrier liquid that is immiscible with the sample and non-wetting of the inner wall of the conduit to reduce instabilities in the apparatus due to undue fluid movement.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: April 14, 1998
    Assignee: Dade International Inc.
    Inventor: Norman Alfred Parris
  • Patent number: 5724142
    Abstract: A method for measuring or controlling the volume of a liquid segment confined within a tube and having a leading edge and a trailing edge. The tube is exposed to radiation at an angle and radiation refracted from the inner surface of the tube is measured at the leading and trailing edges of the segment while the liquid segment is moving through the tube.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: March 3, 1998
    Assignee: Dade International Inc.
    Inventors: Edward Stephen Kaminski, Paul John Zuk