Abstract: A method of assisting recovery of an injury site of brain or spinal cord injury includes providing a therapeutic dose of X-ray radiation to the injury site through an array of parallel microplanar beams. The dose at least temporarily removes regeneration inhibitors from the irradiated regions. Substantially unirradiated cells surviving between the microplanar beams migrate to the in-beam irradiated portion and assist in recovery. The dose may be administered in dose fractions over several sessions, separated in time, using angle-variable intersecting microbeam arrays (AVIMA). Additional doses may be administered by varying the orientation of the microplanar beams. The method may be enhanced by injecting stem cells into the injury site.
Type:
Grant
Filed:
February 10, 2005
Date of Patent:
January 2, 2007
Assignee:
Brookhaven Science Associates, LLC
Inventors:
F. Avraham Dilmanian, John W. McDonald, III
Abstract: A method of serially transferring annihilation information in a compact positron emission tomography (PET) scanner includes generating a time signal for an event, generating an address signal representing a detecting channel, generating a detector channel signal including the time and address signals, and generating a composite signal including the channel signal and similarly generated signals. The composite signal includes events from detectors in a block and is serially output. An apparatus that serially transfers annihilation information from a block includes time signal generators for detectors in a block and an address and channel signal generator. The PET scanner includes a ring tomograph that mounts onto a portion of an animal, which includes opposing block pairs. Each of the blocks in a block pair includes a scintillator layer, detection array, front-end array, and a serial encoder. The serial encoder includes time signal generators and an address signal and channel signal generator.
Type:
Grant
Filed:
October 16, 2003
Date of Patent:
October 24, 2006
Assignee:
Brookhaven Science Associates, LLC
Inventors:
David J. Schyler, Paul O'Connor, Craig Woody, Sachin Shrirang Junnarkar, Veljko Radeka, Paul Vaska, Jean-Francois Pratte, Nora Volkow