Abstract: The present invention provides isolated human heparanase polypeptides, and the isolated polynucleotide molecules that encode them, as well as vectors and host cells comprising such polynucleotide molecules. The invention also provides a method for the identification of an agent that alters heparanase activity.
Type:
Grant
Filed:
February 18, 1999
Date of Patent:
May 14, 2002
Assignee:
Pharmacia and Upjohn Company
Inventors:
Robert Leroy Heinrikson, Michael B. Fairbanks, Ana M. Mildner