Patents Represented by Attorney, Agent or Law Firm Lori K. Kerber
  • Fluorescence-based high throughput screening assays for protein kinases and phosphatases
    Patent number: 6818413
    Abstract: The invention relates to novel fluorescence-based assays for protein kinases and phosphatases which can be used in high throughput screening. The methods of the invention utilize a competitive immunoassay to determine the amount of substrate that is phosphorylated or dephosphorylated during the course of a kinase or phosphatase reaction to yield a product, as well as the phosphorylating or dephosphorylating activity of a kinase or phosphatase.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: November 16, 2004
    Assignee: Pharmacia and Upjohn Company
    Inventors: Dennis E. Epps, Charles K. Marschke