Patents Represented by Attorney Louis Myers

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  • Allogeneic and xenogeneic transplantation
    Patent number: 5876708
    Abstract: Methods of inducing tolerance including administering to the recipient a short course of help reducing treatment or administering a short course and methods of prolonging the acceptance of a graft by administering a short course of an immunosuppressant.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: March 2, 1999
    Assignee: The General Hospital Corporation
    Inventor: David H. Sachs
  • DNA encoding an insulin receptor substrate
    Patent number: 5858701
    Abstract: A substantially pure nucleic acid comprising a sequence encoding an IRS-2 polypeptide, a substantially pure preparation of an IRS-2 polypeptide, and related methods.
    Type: Grant
    Filed: October 3, 1994
    Date of Patent: January 12, 1999
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Morris F. White, Xiao Jian Sun, Jacalyn H. Pierce
  • Transgenically produced antithrombin III
    Patent number: 5843705
    Abstract: This invention relates to transgenically produced human Antithrombin III (tgATIII). The human ATIII produced by the transgenic process of the present invention has a monosaccharide composition which comprises N-acetylgalactosamine (GaINAc) along with fucose, N-acetylglucosamine, galactose, mannose, and N-acetylneuraminic acid/N-glycolyneuraminic acid. The monosaccharide composition differs with that of plasma derived ATIII (phATIII). It has been found that tgATIII has an increased clearance rate when compared to phATIII.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: December 1, 1998
    Assignee: Genzyme Transgenic Corporation
    Inventors: Paul DiTullio, Harry Meade, Edward S. Cole
  • Ikaros polypeptides
    Patent number: 5824770
    Abstract: A purified polypeptide having at least 85% sequence identity with an Ikaros polypeptide or exon.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 20, 1998
    Assignee: The General Hospital Corporation
    Inventor: Katia Georgopoulos
  • Inhibition of signal transduction molecules
    Patent number: 5801149
    Abstract: A peptide capable of inhibiting the interaction of an SH2 domain containing protein with a second protein.
    Type: Grant
    Filed: March 21, 1995
    Date of Patent: September 1, 1998
    Assignee: Joslin D-abetes Center, Inc.
    Inventor: Steven Shoelson
  • E2 binding proteins
    Patent number: 5792833
    Abstract: E2-BP polypeptides, nucleic acids encoding E2-BP polypeptides, and uses thereof.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: August 11, 1998
    Assignee: New England Medical Center Hospitals, Inc.
    Inventors: Elliot J. Androphy, David E. Breiding
  • Reduction of heat transfer between a body and its environment
    Patent number: 5765586
    Abstract: Heat transfer between a body and its surrounding fluidous environment is reduced by placing at least one baffle-insulator adjacent to the body, such that the baffle-insulator which has a thermal conductivity of less than about 5 watts/meter-.degree.K, disturbs, modifies, and/or weakens fluidous environment flow about the body, thus reducing heat transfer between the body and its environment.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: June 16, 1998
    Assignee: Powermass Corporation
    Inventors: Georges Facas, Harry L. Brown
  • Nucleic acid encoding pp60.sup.PIK and the methods of making pp60.sup.PIK
    Patent number: 5650293
    Abstract: A substantially pure nucleic acid comprising a sequence encoding a pp60.sup.PIK peptide and methods of using nucleic acid encoding pp60.sup.PIK to make pp60.sup.PIK polypeptide.
    Type: Grant
    Filed: June 10, 1994
    Date of Patent: July 22, 1997
    Assignee: Joslin Diabetes Center, Inc.
    Inventor: Morris F. White
  • B1k chain of laminin and methods of use
    Patent number: 5610031
    Abstract: Recombinant laminin B1k and fragments thereof.
    Type: Grant
    Filed: October 27, 1993
    Date of Patent: March 11, 1997
    Assignees: The General Hospital Corporation, The State of Oregon Acting By & Thru the State Board . . .
    Inventors: Robert E. Burgeson, David W. Wagman
  • Diabetogene rad: a type II diabetes specific gene
    Patent number: 5589374
    Abstract: Purified DNA including a sequence encoding Diabetogene rad.
    Type: Grant
    Filed: June 11, 1993
    Date of Patent: December 31, 1996
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: C. Ronald Kahn, Christine Reynet
  • KS-laminin and methods of use
    Patent number: 5580960
    Abstract: KS-laminin and a KS-laminin-kalinin adduct are disclosed. The molecules of the invention are useful for promoting the adhesion of keratinocytes to a substrate.
    Type: Grant
    Filed: October 22, 1993
    Date of Patent: December 3, 1996
    Assignee: The General Hospital Corporation
    Inventors: Robert E. Burgeson, Marie-France Champliaud
  • Coronary heart disease treated with 17.beta.oestradiol
    Patent number: 5512557
    Abstract: Use of 17.beta.-oestradiol in the treatment of coronary heart disease.
    Type: Grant
    Filed: October 7, 1993
    Date of Patent: April 30, 1996
    Assignee: National Heart and Lung Institute
    Inventor: Peter Collins