Abstract: Improved position estimation for a square photodetector having terminals at its corners is provided by first estimating an event position in a coordinate system aligned with the diagonals of the square, and then performing a coordinate rotation to provide an estimated position in a coordinate system aligned with the sides of the square. These two steps can also be mathematically combined. It is believed that the improved accuracy of this position determination approach is a result of a greater degree of linearity in charge division between terminals along diagonal axes than along orthogonal axes of a square detector. Flood images provided by this method have been compared to flood images provided by the conventional Anger method, and substantially less image distortion is observed with the present method than with the Anger method.

Abstract: The present invention provides a magnetic sifter that is small in scale, enables three-dimensional flow in a direction normal to the substrate, allows relatively higher capture rates and higher flow rates, and provides a relatively easy method of releasing captured biomolecules. The magnetic sifter includes at least one substrate. Each substrate contains a plurality of slits, each of which extends through the substrate. The sifter also includes a plurality of magnets attached to the bottom surface of the substrate. These magnets are located proximal to the openings of the slits. An electromagnetic source controls the magnitude and direction of magnetic field gradient generated by the magnets. Either one device may be used, or multiple devices may be used in series. In addition, the magnetic sifter may be used in connection with a detection chamber.

Abstract: In a fuel cell assembly (1) comprising a pair of separators (11, 12) each for defining a recess (10) serving as a conduit for a fuel fluid or an oxidizer fluid, a feedthrough conductive path for connecting top and under surfaces of each separator is achieved by a second electroconductive film (36) formed on a side wall of a through-hole (33) extending through each separator (11, 12) in such a manner that the second electroconductive film (36) connects a first electroconductive film (35) constituting a top surface of a protrusion (30) provided in the recess (10) to a third electroconductive film (37) formed on a surface opposite to that formed with the recess (10).

Abstract: A lateral high-voltage depletion-mode device structure in which fingers of semiconductor material are interdigitated with trench gates. Since the effective channel area is proportional to the depth of the trenches, a large amount of active channel area can be achieved for a given surface area.

Abstract: A charge multiplexed position sensing apparatus and method for measuring an incident radiation with the aid of an array of solid-state photosensitive detectors such as an array of avalanche photodiodes (APDs). The solid-state photosensitive detectors multiplex sum terminal(s) and a number of correspondent spatial terminals separately. Sum signal busses are provided to establish separate connections to the sum terminals of each solid-state photosensitive detector. Spatial signal busses interconnect correspondent spatial terminals of all of the solid-state photosensitive detectors such that correspondent spatial terminals are all connected to the same spatial signal bus. The multiplexing circuit triggers on electrical signals corresponding to sum or total voltages generated by the incident radiation.

Abstract: An adaptive transversal filter having tap weights Wj which are products of corresponding tap coefficients Cj and tap gains Mj is provided. A filter control loop controls all of the tap coefficients Cj such that an error signal derived from the filter output is minimized. One or more tap control loops controls a tap gain Mk such that the corresponding tap coefficient Ck satisfies a predetermined control condition. For example, |Ck| can be maximized subject to a constraint |Ck|?Cmax, where Cmax is a predetermined maximum coefficient value. In this manner, the effect of quantization noise on the coefficients Cj can be reduced. Multiple tap control loops can be employed, one for each tap. Alternatively, a single tap control loop can be used to control multiple taps by time interleaving.

Abstract: A method of continuous real-time monitoring and positioning of multi-leaf collimators during on and off radiation exposure conditions of radiation therapy to account for target motion relative to a radiation beam is provided. A prediction algorithm estimates future positions of a target relative to the radiation source. Target geometry and orientation are determined relative to the radiation source. Target, treatment plan, and leaf width data, and temporal interpolations of radiation doses are sent to the controller. Coordinates having an origin at an isocenter of the isocentric plane establish initial aperture end positions of the leaves that is provided to the controller, where motors to position the MLC midpoint aperture ends according to the position and target information. Each aperture end intersects a single point of a convolution of the target and the isocenter of the isocentric plane.

Abstract: An improved two-step replication process for fabrication of porous metallic membranes is provided. A negative of a porous non-metallic template is made by infiltration of a liquid precursor into the template, curing the precursor to form a solid negative, and removing the template to expose the negative. Metal is deposited to surround the exposed negative. Removal of the negative provides a porous metallic membrane having pores which replicate the pores of the original template membrane. The negative is kept immersed in a liquid at all times between removing the template and depositing the metal. This immersion eliminates damage to the negative that would be incurred in drying the negative out between these processing steps. Another aspect of the invention is metallic membranes prepared according to the preceding method. For example, metallic membranes having pores smaller on one side than on the other side of the membrane are provided.