Abstract: An immunological substance detecting reagent is provided which, in the preferred embodiment, employs an immunological homolog specific for the immunological substance to be detected coupled to a water-soluble polymer having a net charge not greater than zero. The water-soluble polymer further has associated a plurality of marker substances such as fluorophore molecules thereby providing a reagent of increased sensitivity for the detection of an antigen-antibody immunological reaction.
Type:
Grant
Filed:
October 19, 1981
Date of Patent:
February 28, 1984
Assignee:
Ortho Diagnostic Systems, Inc.
Inventors:
A. R. M. Azad, Stefan J. Kirchanski, Michael C. Brown