Patents Represented by Attorney M. Reza Savari
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Patent number: 8329884Abstract: This invention provides compositions and methods for detecting Neisseria gonorrhoeae in a sample. This invention also provides related reaction mixtures, kits, systems, and computers.Type: GrantFiled: November 10, 2011Date of Patent: December 11, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Diane Kawa, Shi-Da Lu, Peter Dailey
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Patent number: 8313652Abstract: The present invention includes a container and a method of separating one or more components of interest bound to magnetic particles using centrifugal forces.Type: GrantFiled: November 12, 2009Date of Patent: November 20, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Heinz Michael Hein, Emad Sarofim, Lotar Schenk, Hans-Peter Wahl
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Patent number: 8285497Abstract: A method of gravimetric volume determination is described in which a load cell can be calibrated either outside of an analytic analyzer for gravimetric calibration of the analyzer, or in a fully automated manner inside the analyzer.Type: GrantFiled: September 15, 2009Date of Patent: October 9, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Hans-Rudolf Bachmann, Joerg Burmester, Philipp Kull, Daniel Ott, Markus Thiel
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Patent number: 8271230Abstract: Disclosed herein are methods for monitoring a thermoelectric heating and cooling device (103, 203, 303) of a system (100, 200, 300) for cycling liquid reaction mixtures through a series of temperature excursions, and such systems adapted to perform these methods. A first quantity being either an electric current or an electric voltage is applied to the heating and cooling device (103, 203) or a portion (314) thereof (303), and a second quantity being either the non-selected first quantity or temperature is measured to obtain a first test value. The selected first quantity is applied to another thermoelectric heating and cooling device (104, 204) or another portion (315) of the first device (303), and the second quantity is measured to obtain a second test value. Comparison of the first and second test values yields a monitoring value which is compared with a pre-defined threshold value to obtain a monitoring result.Type: GrantFiled: December 15, 2009Date of Patent: September 18, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Paul Federer, Daniel Bommer, Guido Grueter, Stefan Job, Thomas Schlaubitz
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Patent number: 8239137Abstract: Subjects of the invention are a method for determination of an analyte using a particular algorithm based on a mathematical model for transforming measurement data into a growth curve and an analytical instrument comprising a computing unit for more precise determination of an analyte.Type: GrantFiled: December 15, 2006Date of Patent: August 7, 2012Assignee: Roche Molecular Systems, Inc.Inventor: Rolf Knobel
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Patent number: 8202975Abstract: This invention provides compositions and methods for detecting HPV in a sample. This invention also provides related kits, systems, and computers.Type: GrantFiled: September 20, 2011Date of Patent: June 19, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Janet Kornegay, Carrie L. Aldrich, Stephen G. Will
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Patent number: 8198422Abstract: This invention provides compositions and methods for detecting HPV in a sample. This invention also provides related kits, systems, and computers.Type: GrantFiled: September 20, 2011Date of Patent: June 12, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Janet Kornegay, Carrie L. Aldrich, Stephen G. Will
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Patent number: 8198423Abstract: This invention provides compositions and methods for detecting HPV in a sample. This invention also provides related kits, systems, and computers.Type: GrantFiled: September 20, 2011Date of Patent: June 12, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Janet Kornegay, Carrie L. Aldrich, Stephen G. Will
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Patent number: 8197750Abstract: The invention relates to devices and methods for the identification of test tubes in a test tube rack using RFID technology.Type: GrantFiled: January 16, 2009Date of Patent: June 12, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Heinz Trueeb, Armin Birrer, Thomas Brauner
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Patent number: 8158349Abstract: The invention concerns a method for isolating and purifying nucleic acids from a sample and a device that is suitable therefore.Type: GrantFiled: January 14, 2011Date of Patent: April 17, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Dirk Block, Ruediger Haenel, Joerg Kleiber, Manuela Poignee-Heger, Thomas Walter, Ralf Zielenski
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Patent number: 8137616Abstract: The invention is directed to a system for performing multi-color real time PCT, comprising a flexible real time PCT instrument and a specific composition or reaction mixture for performing multiplex PCR: In particular, the present invention is directed to a composition or reaction mixture which comprises at least 3, preferably 4-5 and most preferably exactly 4 pairs of FRET hybridization probes. Each pair of said hybridization probes consists of a FRET donor probe carrying a FRET donor moiety and a FRET acceptor probe carrying a FRET acceptor moiety having an emission maximum between 550 and 710 nm.Type: GrantFiled: April 1, 2004Date of Patent: March 20, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Gregor Sagner, Ingrid Bechler, Jochen Bolte, Dieter Heindl, Hans-Peter Josel, Martin Gutekunst, Rudolf Sebl, Christoph Mueller
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Patent number: 8110396Abstract: The invention relates to a thermocycler module for heating and/or cooling of a thermocycling device comprising a thermal switch, a heating block and a heat sink. The thermal switch comprises a thermoconducting liquid, e.g. a magnetic fluid or a liquid metal, and a stimulating unit, e.g. a magnetic unit or a Lorentz-force unit, for moving the thermoconducting liquid. The movement of the thermoconducting liquid provides, in an on-state of the thermal switch, a thermal connection between the heating block and the heat sink.Type: GrantFiled: May 18, 2009Date of Patent: February 7, 2012Assignee: Roche Molecular Systems, Inc.Inventors: Daniel Bommer, Thomas Schlaubitz
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Patent number: 8062884Abstract: The invention refers to a handling kit for analyzing a liquid sample, especially by nucleic acid amplification, comprising a disposable sample holding and processing device (1) dimensioned for use in an apparatus for analyzing a liquid sample, and a sample transfer tip (12) for transferring liquid into the disposable device (1), the disposable device (1) having a sample preparation chamber (10) which has an outlet (9) and an insertion opening (16) which is adapted to receive the sample transfer tip (12), the insertion opening and the sample transfer tip (12) being dimensioned in such a way that inserting the sample transfer tip (12) into an insertion position in the sample preparation chamber (10) causes a tight seal between an outer wall (40) of the sample transfer tip (12) and an inner wall (41) of the sample preparation chamber (10), the disposable device (1) having a vent (31) for venting the sample preparation chamber (10).Type: GrantFiled: July 5, 2007Date of Patent: November 22, 2011Assignee: Roche Molecular Systems, Inc.Inventor: Emad Sarofim
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Patent number: 8058423Abstract: This invention provides compositions and methods for detecting HPV in a sample. This invention also provides related kits, systems, and computers.Type: GrantFiled: December 10, 2008Date of Patent: November 15, 2011Assignee: Roche Molecular Systems, Inc.Inventors: Janet Kornegay, Carrie L. Aldrich, Stephen Gordon Will