Patents Represented by Attorney Margaret A. Fish & Neave Pierri

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  • Method for augmenting fetal hemoglobin
    Patent number: RE36080
    Abstract: A method is provided for inhibiting the .gamma. to .beta.-globin switching in subjects afflicted with .beta.-globin disorders. The method is particularly adapted for ameliorating the clinical symptoms of sickle cell anemia by periodically introducing butyrate, .Iadd..alpha.-amino-n-butyric acid, .Iaddend.or .?.certain isomers, homologs, analogs or chemical variations thereof,.!. .Iadd.isobutyramide .Iaddend.into the bloodstream of the subject prior to natural completion of the switching process.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: February 2, 1999
    Assignee: Children's Hospital Medical Center of Northern California
    Inventor: Susan P. Perrine