Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture. Quinoline and quinolone compounds are useful as photosensitizers in this method. With certain photosensitizers a blocking agent may also be employed.

Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.

Abstract: An improved dialysis apparatus and method wherein a dialysis delivery system delivers dialysate to a dialyzer through an external dialysate line with a dialyzer inlet connector and a dialysate waste system removes spent dialysate from the dialyzer through an external spent dialysate line with a dialyzer outlet connector. A bypass block comprises a first bypass block connector adapted to connect to the dialyzer inlet connector and a second bypass block connector adapted to connect to the dialyzer outlet connector and a conduit interconnecting the first bypass block connector and the second bypass block connector with a check valve located intermediate the first and second bypass block connectors and oriented to permit fluid flow only from the first bypass block connector to the second bypass block connector.

Abstract: A method and apparatus for cleaning of a dialysate circuit located downstream of the dialyzer in a dialysis machine is described. The method comprises injecting a cleaning agent into the dialysis machine at a point between the dialyzer inlet port and the downstream dialysate circuit in an amount sufficient to substantially reduce the deposit in said downstream dialysate circuit; permitting flow of the agent towards the downstream dialysate circuit; and substantially preventing flow of the agent toward the dialyzer inlet port. The injection adaptor apparatus comprises an injection connector downstream of a backflow prevention valve, and two flanking tubing connectors. The apparatus is inserted at a point downstream of the dialyzer inlet port, and cleaning agent is injected into the injection connector. An adaptor to facilitate handling of cleaning agent during manual agent injection is also described. Additionally, an automated agent injection apparatus is described.