Patents Represented by Attorney, Agent or Law Firm Mark A. Litman & Assoc.
  • Patent number: 6328446
    Abstract: A method of making an optical element that includes a thermoplastic power portion, the method including laminating a first thermoplastic sheet to one side of a functional film, laminating a second thermoplastic sheet to a second side of the functional film, and affixing either the first thermoplastic sheet or the second thermoplastic sheet to the power portion, with the other of the first or second thermoplastic sheets being open to atmosphere.
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: December 11, 2001
    Assignee: Vision-Ease Lens, Inc.
    Inventors: Sujal Bhalakia, Thomas J. Moravec
  • Patent number: 6272370
    Abstract: The present invention comprises a device and method for targeted drug delivery, and especially intracranial inflsion or retroperfusion drug delivery using nonlinear magnetic stereotaxis in combination with magnetic resonance (MR) imaging and/or X-ray visualization. An MR-visible and/or X-ray visible drug delivery device is positioned by non-linear magnetic stereotaxis at a site such as an intracranial target site, its location is verified via MR imaging, and it is then used to deliver a biologically active material such as a diagnostic or therapeutic drug solution into that site (such as the brain) at constant or variable rates. The spatial distribution kinetics of the injected or infised drug agent may be monitored quantitatively and non-invasively using real-time MR-imaging such as water proton directional diffusion MR imaging, to establish the efficacy of targeted drug delivery.
    Type: Grant
    Filed: August 7, 1998
    Date of Patent: August 7, 2001
    Assignees: The Regents of University of Minnesota, Virginia Commonwealth University
    Inventors: George T. Gillies, John Kucharczyk, William C. Broaddus, Richard Latchaw
  • Patent number: 6261756
    Abstract: The present invention refers to a light-sensitive silver halide multilayer color photographic element having a support base and coated thereon blue-, green- and red-sensitive silver halide emulsion layers respectively associated with non-diffusing yellow, magenta and cyan dye-forming couplers, wherein at least one green-sensitive layer contains a 2-equivalent 3-anilino-4-phenylthio-5-pyrazolone magenta coupler and a 4-(4-hydroxy-phenylazo)-5-pyrazolone colored magenta coupler. The multilayer color photographic element of the present invention presents an improved speed and contrast, without a detrimental effect on the other sensitometric properties, such as Dmin and Dmax.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: July 17, 2001
    Assignee: Terrania, S.p.A.
    Inventors: Raffaella Biavasco, Emilio Prosperi, Roberto Sardelli
  • Patent number: 6258522
    Abstract: The present invention relates to a light-sensitive emulsion, and a light-sensitive photographic material containing the same, comprising silver bromoiodide grains of a core shell structure comprising a) an inner core consisting essentially of silver bromide or silver bromoiodide, the silver iodide content of said inner core being within the range of 0 to 10 mole %, and b) a plurality of shells consisting essentially of silver bromide or silver bromoiodide, wherein a pure silver iodide phase representing from 0.1 to 5 mole % of the total silver halide grain content is interposed between two adjacent shells, and wherein at least one of said adjacent shells has a silver iodide content higher than 5 mole %.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: July 10, 2001
    Assignee: Ferrania S.p.A.
    Inventors: Mario Mariotti, Stefania Ghirardo, Giuseppe Rocca, Mauro Avidano, Alessandro Gunnella, Ezio Astengo
  • Patent number: 6242168
    Abstract: The present invention relates to a light-sensitive silver halide color multilayer photographic material which comprises a support base having coated thereon at least three red-sensitive emulsion layers having different sensitivity, at least three green-sensitive emulsion layers having different sensitivity, and at least two yellow-sensitive emulsion layers having different sensitivity, wherein (a) a core-shell silver halide emulsion having an average silver iodide content lower than 10% mol is present in at least one of the lowest sensitive red-, green- and yellow layers, (b) a yellow dye forming malonodiamide DIR coupler having in the coupling position thereof a 4,7-dihalogen-2-benzotriazolyl group is present in both the medium sensitive red- and green-sensitive layers, and (c) a yellow dye forming DIR coupler having a 1,2,4-triazolyl group attached to the coupling position, such 1,2,4-triazolyl group comprising a hydrolizable alkoxy- or aryloxy-carbonyl group attached to a benzytlthio substituent on the
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: June 5, 2001
    Assignee: Ferrania SpA
    Inventors: Mauro Avidano, Raffaella Biavasco, Diego Brignone, Giuseppe Rocca, Luisa Tavella
  • Patent number: 6197485
    Abstract: A photographic assemblage comprising a silver halide photographic light-sensitive element comprising at least one sulfur and gold sensitized silver halide emulsion layer, said element comprising chlorinated s-triazine hardeners and photographically useful chemical compounds containing cyano groups, and a closed vessel in which the element is closed and stored at a constant relative humidity, is protected against HCN gas, which may evolve from photographic addenda included in the light-sensitive element to cause fog in the silver halide emulsion layers, by the addition of a palladium compound, in a silver halide emulsion layer and/or an adjacent layer thereto, as scavenger for HCN gas released from the element.
    Type: Grant
    Filed: September 27, 1993
    Date of Patent: March 6, 2001
    Assignee: Minnesota Mining & Manufacturing Company
    Inventors: Luigi Cellone, Brunella Fornasari, Giovanni Giusto
  • Patent number: 6143922
    Abstract: The present invention relates to a novel composition of diols, said composition of diols comprisingHO--(H.sub.3 C)R.sup.4 C--Q--CR.sup.5 (CH.sub.3)--OHwherein Q is a diaryl group comprising two aryl groups linked together directly (as in biphenyl) or bridged by an oxygen atom, sulfur atom or methyl group,R.sup.4 and R.sup.5 are independently selected from the group consisting of hydrogen and lower alkyl groups (e.g., methyl, ethyl, propyl and butyl, most preferably methyl). The diols will usually be provided as compositions which comprise either:a solution of the diols, with the diols comprising more than 99% by weight solids of the solution, and whichdiol has less than 1% by weight of impurity selected from the group consisting essentially of monoaryl hydroxy compounds, especially monoaryl monohydroxy compounds, and monoaryl dihydroxy compounds where only one hydroxy group is attached directly to the aryl ring.
    Type: Grant
    Filed: October 7, 1998
    Date of Patent: November 7, 2000
    Inventor: Boris A. Zaitsev