Patents Represented by Attorney, Agent or Law Firm Mark A. Winter
  • 3-indazolyl-4-pyridylisothiazoles
    Patent number: 7932274
    Abstract: The present invention provides 3-indazoyl-4-pyridylisothiazoles or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and methods of using the same, as well as processes for preparing the same, and intermediates thereof.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: April 26, 2011
    Assignee: Eli Lilly and Company
    Inventors: Thomas Charles Britton, Veronique Dehlinger, Adam Michael Fivush, Sean Patrick Hollinshead, Benjamin Paul Vokits
  • Pyridyl derivatives and their use as mGlu5 antagonists
    Patent number: 7915424
    Abstract: The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: March 29, 2011
    Assignee: Eli Lilly and Company
    Inventors: Francisco Javier Agejas-Chicharro, Bruce Anthony Dressman, Jose Antonio Martinez Perez, James Allen Monn, Mohammad Sadegh Zia-Ebrahimi, Sonia Gutierrez Sanfeliciano, Steven Marc Massey, Steven Scott Henry
  • 1-(hetero)aryl-3-amino-pyrrolidine derivatives for use as mGluR3 antagonists
    Patent number: 7868014
    Abstract: The present invention relates to compounds of the Formula (I) which are useful for treating conditions associated with mGluR3 receptors, such as depression, schizophrenia and migraine, pharmaceutical compositions thereof, and methods of using the same.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: January 11, 2011
    Assignee: Eli Lilly and Company
    Inventors: Thomas Charles Britton, Veronique Dehlinger, Colin Peter Dell, Bruce Anthony Dressman, Jason Kenneth Myers, Eric Samuel Nisenbaum
  • Potentiators of glutamate receptors
    Patent number: 7858646
    Abstract: The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: December 28, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Dana Rae Benesh, Maria-Jesus Blanco-Pillado, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsäter, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Cyclopropanecarboxylate esters of acyclovir
    Patent number: 7846937
    Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, methods of using the same, processes for preparing the same, and intermediates thereof.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: December 7, 2010
    Assignee: Eli Lilly and Company
    Inventors: David Michael Bender, James Ray McCarthy
  • Potentiators of glutamate receptors
    Patent number: 7816523
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: October 19, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Potentiators of glutamate receptors
    Patent number: 7803938
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: September 28, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Micheal Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Imidazole carboxamides
    Patent number: 7754742
    Abstract: The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: July 13, 2010
    Assignee: Eli Lilly and Company
    Inventors: Albert Khilevich, Bin Liu, Daniel Ray Mayhugh, Jeffrey Michael Schkeryantz, Deyi Zhang
  • Potentiators of glutamate receptors
    Patent number: 7678794
    Abstract: The present invention provides a compound of formula (I): pharmaceutical compositions thereof, and methods of using the same, processes for preparing the same, and intermediates thereof.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: March 16, 2010
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang
  • Aminomethyl-azacycle derivatives as inhibitors of monoamine uptake
    Patent number: 7615648
    Abstract: The present invention provides compounds of formula (I) wherein A is (1), (2), (3), (4), (5), (6) or (7) and wherein R1, R7, y and Ar1 are defined herein. The compounds are inhibitors of the uptake of one or more monoamines selected from serotonin, norepinephrine and dopamine and, as such, may be useful in the treatment of disorders of the central and/or peripheral nervous system.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: November 10, 2009
    Assignee: Eli Lilly and Company
    Inventors: John Richard Harris, Barry Peter Clark, Peter Thaddeus Gallagher, Maria Ann Whatton
  • Potentiators of glutamate receptors
    Patent number: 7598423
    Abstract: This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: October 6, 2009
    Assignee: Eli Lilly and Company
    Inventors: Thomas Daniel Aicher, Guillermo S. Cortez, Todd Michael Groendyke, Albert Khilevich, James Allen Knobelsdorf, Fredrik Pehr Marmsater, Jeffrey Michael Schkeryantz, Tony Pisal Tang, Nicholas Andrew Magnus
  • Potentiators of glutamate receptors
    Patent number: 6800651
    Abstract: The present invention relates to potentiators of metabotropic glutamate receptor function and specifically provides compounds of formula I, compositions thereof and methods of using the same.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: October 5, 2004
    Assignee: Eli Lilly and Company
    Inventors: Darrell Stephen Coleman, Gunnar Erik Jagdmann, Kirk Willis Johnson, Michael Parvin Johnson, Thomas Hallett Large, James Allen Monn, Darryle Darwin Schoepp, Thomas Charles Britton, Steven Scott Henry, Joseph Patrick Tizzano