Abstract: A breast crease comforter decreases pain and promotes healing during and after radiation therapy to the breast. The skin crease between the breast and the torso is typically exposed to daily friction, sheer, and moisture. When the breast is also compromised by radiation therapy, these various insults may combine to cause skin breakdown and excoriation, including resultant pain. The breast crease comforter intervenes between the underside of the breast and the torso to protect and pad this sensitive crease area when compromised by radiation therapy. The breast crease comforter may also be used to treat other conditions besides vulnerable skin resulting from radiation therapy to the breast or torso. The breast crease comforter may also be combined with the bottom of a conventional bra.