Patents Represented by Attorney Mark J. Cohen

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  • Synthesis of quaternary salt compounds
    Patent number: 8168829
    Abstract: The present invention is directed to a process, having a reduced environmental impact, for preparing phenylamino substituted quaternary salt compounds that are CCR2 antagonists.
    Type: Grant
    Filed: October 22, 2008
    Date of Patent: May 1, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: David C. Palmer, Sergio Casco-Cancian, Tong Xiao, Kirk L. Sorgi, Armin Roessler, Anita Vladislavic, Roger Faessler
  • 2,7-substituted octahydro-1H-pyrido[1,2-a]pyrazine derivatives as ligands for serotonin receptors
    Patent number: 7220753
    Abstract: Substituted pyrido[1,2-a]pyrazines of general formula I; wherein Ar and Ar1 represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO2, CHOH, C?O, or —(CR3R4); and n is 0–2, as well as precursors thereto, are ligands for dopamine receptor subtypes and serotonin (5HT) within the body and are therefore useful in the treatment of disorders of the dopamine and serotonin systems:
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: May 22, 2007
    Assignee: Pfizer Inc.
    Inventors: Kishor A. Desai, Anton F. Fliri, Mark A. Sanner
  • Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors
    Patent number: 6867184
    Abstract: The present invention provides methods of treating diabetic cardiomyopathy, the methods comprising administering to a patient having or at risk of having diabetic cardiomyopathy a therapeutically effective amount of a glycogen phosphorylase inhibitor.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: March 15, 2005
    Assignee: Pfizer, Inc.
    Inventor: Judith L. Treadway